Cognitive Dysfunction and Age-Related Macular Degeneration

被引：24

作者：

Rozzini, Luca ^{[1
]}

Riva, Maddalena ^{[1
]}

Ghilardi, Nausica ^{[2
]}

Facchinetti, Paola ^{[1
]}

Forbice, Eliana ^{[2
]}

Semeraro, Francesco ^{[2
]}

Padovani, Alessandro ^{[1
]}

机构：

[1] Univ Brescia, Dept Neurol, I-25100 Brescia, Italy

[2] Univ Brescia, Dept Ophthalmol, I-25100 Brescia, Italy

来源：

AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS | 2014年 / 29卷 / 03期

关键词：

cognitive impairment; dementia; neuro-ophtalmology; vision; drusen; ALZHEIMERS ASSOCIATION WORKGROUPS; DIAGNOSTIC GUIDELINES; NATIONAL INSTITUTE; DISEASE; DEMENTIA; DRUSEN; IMPAIRMENT; RISK; ATHEROSCLEROSIS; RECOMMENDATIONS;

D O I：

10.1177/1533317513517032

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Several previous studies showed that age-related macular degeneration (AMD) and Alzheimer's disease (AD) share common risk factors and histopathology changes, and there is epidemiological evidence linking AMD to cognitive impairment. We tested this theory in 51 patients with late-stage AMD and 24 controls by analyzing their neuropsychological profiles. In this study, data showed that patients affected by late-stage AMD have a worse global cognitive function than those of the controls and, in particular, show worse performances in memory tasks. Moreover, patients affected by the dry form of AMD are significantly impaired in executive functions in addition to memory. Data support the hypothesis of a possible association between AMD and cognitive impairment. In particular, patients affected by the dry form of AMD may be at greater risk of developing subsequent dementia.

引用

页码：256 / 262

页数：7

共 40 条

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