The dipolar route to naphtho[2,1-c]isoxazoles from the Baylis-Hillman adducts of 2-alkynylbenzaldehydes

被引：23

作者：

Ji, Sang-Hoon ^{[1
]}

Hong, Wan Pyo ^{[1
]}

Ko, Seung Ho ^{[1
]}

Lee, Kee-Jung ^{[1
]}

机构：

[1] Hanyang Univ, Dept Chem Engn, Organ Synth Lab, Seoul 133791, South Korea

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2006年 / 43卷 / 03期

关键词：

D O I：

10.1002/jhet.5570430344

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new synthesis of 4-carbomethoxynaphtho[2,1-c]isoxazoles 4a-d from methyl 3-(alkynylphenyl)-2-nitromethyl-2-propenoates 2a-d by the intramolecular nitrile oxide cycloaddition is described. The latter are readily obtained from 2-alkynylbenzaldehydes through the Baylis-Hillman adduct acetates 1a-d followed by nucleophilic substitution of nitrite anion.

引用

页码：799 / 801

页数：3

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