Structural Imaging in Cluster Headache

被引:16
作者
Naegel, Steffen [1 ]
Holle, Dagny [1 ]
Obermann, Mark [1 ]
机构
[1] Univ Duisburg Essen, Dept Neurol, D-45122 Essen, Germany
关键词
Cluster headache; Voxel-based morphometry; DTI; TBSS; Neuronal plasticity; Hypothalamus; BRAIN GRAY-MATTER; MIGRAINE PATIENTS; PAIN; DECREASE; NETWORK; VOLUME;
D O I
10.1007/s11916-014-0415-6
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Cluster headache is a rare primary headache disorder and the most common trigeminal-autonomic cephalalgia. Even though it has been extensively studied, its pathophysiology remains nebulous. Over the last two decades, cerebral imaging has increasingly been used to aid the investigation of pain and headache disorders. Pioneering work using magnetic resonance-based, voxel-based morphometry depicted an isolated increase of grey matter in the posterior hypothalamus and thereby reconfirmed the most commonly accepted pathophysiological concept. More recent works demonstrate structural changes across multiple structures related to pain processing, sensory integration, and emotional evaluation. These changes do not seem to be static, but rather appear to be dynamic in nature as they change over the course of the disease. This was interpreted as a reflection of the plasticity of the human brain and should guide future thoughts towards a more complex pathophysiological model involving a maladaptive pain modulatory network.
引用
收藏
页数:8
相关论文
共 50 条
[41]   Cluster headache [J].
Mathew, NT .
SEMINARS IN NEUROLOGY, 1997, 17 (04) :313-323
[42]   Cluster Headache [J].
van Kleef, Maarten ;
Lataster, Arno ;
Narouze, Samer ;
Mekhail, Nagy ;
Geurts, Jose W. ;
van Zundert, Jan .
PAIN PRACTICE, 2009, 9 (06) :435-442
[43]   Cluster headache [J].
Rolf Salvesen .
Current Treatment Options in Neurology, 1999, 1 (5) :441-449
[44]   Cluster headache [J].
Elizabeth Leroux ;
Anne Ducros .
Orphanet Journal of Rare Diseases, 3
[45]   Cluster headache [J].
Ducros, A ;
Bousser, MGN .
ANNALES DE MEDECINE INTERNE, 2003, 154 (07) :468-474
[46]   Cluster headache and cluster variants [J].
Marc E. Lenaerts .
Current Treatment Options in Neurology, 2003, 5 (6) :455-466
[47]   Cluster Headache and Insular Glial Tumor [J].
Tekgol Uzuner, Gulnur ;
Ertan, Bengu ;
Uzuner, Nevzat .
JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, 2015, 32 (01) :183-187
[48]   Clinical description and treatment of cluster headache [J].
Valade, Dominique .
SANG THROMBOSE VAISSEAUX, 2007, 19 (06) :311-317
[49]   Migraine and cluster headache - the common link [J].
Vollesen, Anne Luise ;
Benemei, Silvia ;
Cortese, Francesca ;
Labastida-Ramirez, Alejandro ;
Marchese, Francesca ;
Pellesi, Lanfranco ;
Romoli, Michele ;
Ashina, Messoud ;
Lampl, Christian .
JOURNAL OF HEADACHE AND PAIN, 2018, 19 :89
[50]   Cluster headache: from treatment to pathophysiology [J].
Bussone, Gennaro .
NEUROLOGICAL SCIENCES, 2008, 29 (Suppl 1) :S1-S6