Acid-Base and Electrolyte Managements in Chronic Kidney Disease and End-Stage Renal Disease: Case-Based Discussion

被引:5
作者
Lin, Jing [2 ]
Cheng, Zhen [3 ]
Ding, Xiaoqiang [2 ]
Qian, Qi [1 ]
机构
[1] Mayo Clin, Coll Med, Dept Med, Div Nephrol & Hypertens, 200 First St SW, Rochester, MN 55905 USA
[2] Fudan Univ, Zhongshan Hosp, Dept Nephrol, Shanghai, Peoples R China
[3] Nanjing Univ, Jinling Hosp, Sch Med, Natl Clin Res Ctr Kidney Dis, Nanjing, Jiangsu, Peoples R China
关键词
Chronic kidney disease; End-stage renal disease; Metabolic acidosis; Metabolic alkalosis; Hypoxia; Hemodialysis; SERUM BICARBONATE LEVELS; MAINTENANCE HEMODIALYSIS-PATIENTS; DIALYSATE SODIUM CONCENTRATION; METABOLIC-ACIDOSIS; PRACTICE PATTERNS; PATIENTS INCREASES; CARDIAC-ARREST; SUDDEN-DEATH; RISK-FACTORS; MORTALITY;
D O I
10.1159/000485155
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Acid-base and electrolyte alterations are common in patients with chronic kidney disease (CKD) and end-stage kidney failure (ESRD). The alterations become more complex as CKD advances to ESRD, leading to morbidity and mortality. Three cases are presented illustrating some key prototypic features in CKD and ESRD. Each is accompanied by discussion of pathophysiology, diagnosis, and treatment options. Newer investigational results are integrated into the existing body of knowledge. Although rigorous assessment of various dialysis prescriptions is scanty, in its current state, instituting a well thought-out, multi-pronged management plan to minimize CKD/ESRD and dialysis-related electrolyte and acid-base disruptions is appropriate. There is a pressing need for prospective interventional trials in the future. (c) 2018 S. Karger AG, Basel
引用
收藏
页码:179 / 186
页数:8
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