AN APPROACH TO THE SYNTHESIS OF NOVEL DIHYDROINDOLES BEARING ELECTRON-WITHDRAWING GROUPS AT C-2 POSITION

被引：1

作者：

Okabe, Fumi ^{[1
]}

Maruoka, Hiroshi ^{[1
]}

Takasu, Masaru ^{[1
]}

Masumoto, Eiichi ^{[1
]}

Fujioka, Toshihiro ^{[1
]}

Yamagata, Kenji ^{[1
]}

机构：

[1] Fukuoka Univ, Fac Pharmaceut Sci, Jonan Ku, Fukuoka 8140180, Japan

来源：

HETEROCYCLES | 2014年 / 88卷 / 01期

关键词：

Furan; Diels-Alder Reaction; Indoline; Diazo Compound; Insertion Reaction; CHOLESTEROL ACYLTRANSFERASE INHIBITOR; CATALYZED REACTION; ACYL-COA; INDOLES; DERIVATIVES; HETEROCYCLES; RING;

D O I：

10.3987/COM-13-S(S)21

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of novel dihydroindoles 8a-d and 9a-d bearing electron-withdrawing groups at C-2 position is presented. The key step of this approach is an efficient intramolecular Diels-Alder reaction of N-alkenylated 2-amino-3-furancarbonitriles 4a-d and 5a-d.

引用

页码：675 / 687

页数：13

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