Expanding Donor Selection and Recipient Indications for Living Donor Liver Transplantation

被引：7

作者：

Moghe, Akshata ^{[1
]}

Ganesh, Swaytha ^{[2
]}

Humar, Abhinav ^{[3
]}

Molinari, Michele ^{[4
]}

Jonassaint, Naudia ^{[5
]}

机构：

[1] Univ Pittsburgh, Med Ctr, Div Gastroenterol Hepatol & Nutr, Dept Med, Mezzanine Level,C Wing,PUH 200 Lothrop St, Pittsburgh, PA 15213 USA

[2] Univ Pittsburgh, Med Ctr, Living Donor Liver Transplantat Program, Dept Med,Ctr Liver Dis, 3471 Fifth Ave,900 Kaufmann Bldg, Pittsburgh, PA 15213 USA

[3] Univ Pittsburgh, Med Ctr, Div Abdominal Transplantat Surg, Thomas E Starzl Transplantat Inst,UPMC Montefiore, Seventh Floor N723,3459 Fifth Ave, Pittsburgh, PA 15213 USA

[4] Univ Pittsburgh, Med Ctr, Dept Surg, UPMC Montefiore, N761,3459 Fifth Ave, Pittsburgh, PA 15213 USA

[5] Univ Pittsburgh, Med Ctr, Div Gastroenterol Hepatol & Nutr, Dept Med,Ctr Liver Dis, 3471 Fifth Ave,900 Kaufmann Bldg, Pittsburgh, PA 15213 USA

来源：

CLINICS IN LIVER DISEASE | 2021年 / 25卷 / 01期

关键词：

Living donor; Liver transplant; Extended criteria; Transplant oncology; LONG-TERM SURVIVAL; HEPATOCELLULAR-CARCINOMA; HEPATIC STEATOSIS; UNITED-STATES; CRITERIA; IMPACT; CHOLANGIOCARCINOMA; METASTASES; GRAFT; MILAN;

D O I：

10.1016/j.cld.2020.08.011

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

There is an acute shortage of deceased donor organs for liver transplantation in the United States. Nearly a third of patients either die or become too sick for transplant while on the transplant waitlist. Living donor liver transplantation (LDLT) bridges the gap between demand and supply of organs for liver transplantation. This article reviews current living donor selection criteria, and avenues for expansion of criteria with novel surgical techniques and ongoing outcomes research. Ways in which institutions can establish and expand LDLT programs using the Living Donor Champion model are discussed. Efforts to expand recipient indications for LDLT are described. © 2020 Elsevier Inc.

引用

页码：121 / 135

页数：15

共 71 条

[1] Status of Adult Living Donor Liver Transplantation in the United States Results from the Adult-To-Adult Living Donor Liver Transplantation Cohort Study [J].