A spatially explicit model of inverse colony formation of cellulolytic biofilms

被引：9

作者：

Eberl, H. J. ^{[1
]}

Jalbert, E. M. ^{[1
]}

Dumitrache, A. ^{[2
]}

Wolfaardt, G. M. ^{[3
]}

机构：

[1] Univ Guelph, Dept Math & Stat, 50 Stone Rd East, Guelph, ON N1G 2W1, Canada

[2] Oak Ridge Natl Lab, Biosci Div, POB 2008 MS-6038, Oak Ridge, TN 37831 USA

[3] Stellenbosch Univ, Dept Microbiol, Private Bag X1, ZA-7602 Matieland, South Africa

来源：

BIOCHEMICAL ENGINEERING JOURNAL | 2017年 / 122卷

基金：

加拿大自然科学与工程研究理事会;

关键词：

Cellulolytic biofilm; Computer simulations; Mathematical model; Inverse colony growth; Traveling waves; CLOSTRIDIUM-THERMOCELLUM BIOFILMS; DIFFERENTIAL-EQUATIONS; DEGRADATION; SIMULATION; DERIVATION; DYNAMICS; CULTURES;

D O I：

10.1016/j.bej.2017.03.007

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

We propose a spatially explicit mathematical model for the formation of cellulolytic biofilms. It consists of a highly nonlinear degenerate coupled PDE-ODE system for the bacteria that colonise the cellulosic substratum, and for the carbon source that is immobilised in the reactive substratum. Computer simulations show that the model is able to reproduce important features of cellulolytic biofilms that have been reported in the experimental literature. These include the formation of inverse colonies, crater-like colonies, degradation of paper chads at constant speed (which correspond to a traveling wave solution of the model), and temporal CO2 production pattern. (C ) 2017 Elsevier B.V. All rights reserved.

引用

页码：141 / 151

页数：11

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