Consensus on the treatment of alopecia areata - Brazilian Society of Dermatology

被引:29
|
作者
Ramos, Paulo Muller [1 ]
Anzai, Alessandra [2 ]
Duque-Estrada, Bruna [3 ]
Melo, Daniel Fernandes [4 ]
Sternberg, Flavia [5 ]
Nogueira Santos, Leopoldo Duailibe [6 ,7 ]
Alves, Lorena Dourado [8 ]
Mulinari-Brenner, Fabiane [9 ]
机构
[1] Univ Estadual Paulista, Dept Dermatol & Radiotherapy, Botucatu, SP, Brazil
[2] Univ Sao Paulo, Dept Dermatol, Sao Paulo, SP, Brazil
[3] Santa Casa Misericordia Rio de Janeiro, Inst Dermatol Prof Rubem David Azulay, Ctr Estudos Cabelos, Rio De Janeiro, RJ, Brazil
[4] Univ Estado Rio de Janeiro, Dept Dermatol, Rio De Janeiro, RJ, Brazil
[5] Univ Fed Sao Paulo, Dept Dermatol, Sao paulo, SP, Brazil
[6] Santa Casa Misericordia Sao Paulo, Dept Med, Sao Paulo, SP, Brazil
[7] Hosp Servidor Publ Municipal, Dept Dermatol & Allergol, Sao Paulo, SP, Brazil
[8] Univ Fed Golas, Dept Trop Med & Dermatol, Goiania, Go, Brazil
[9] Univ Fed Parana, Dept Clin Med, Curitiba, Parana, Brazil
关键词
Adrenal cortex hormones; Alopecia areata; Consensus; Methotrexate; Therapeutics; INTRALESIONAL TRIAMCINOLONE ACETONIDE; TREATMENT OPTIONS; MANAGEMENT; EFFICACY; METHOTREXATE; THERAPY; UPDATE; SAFETY; PREVENTION; MINOXIDIL;
D O I
10.1016/j.abd.2020.05.006
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: Alopecia areata is a highly frequent disease with an impact on quality of life and several treatment options with little clinical confirmatory evidence. Objective: To disseminate the recommendations of Brazilian dermatologists with expertise in the treatment of alopecia areata. Methods: Eight specialists with expertise in alopecia areata from different university centers were appointed by the Brazilian Society of Dermatology to reach a consensus on its treatment. Based on the adapted DELPHI methodology, the relevant elements were considered; then, an analysis of recent literature was carried out and the consensus was written down. Consensus on the management of alopecia areata was defined with the approval of at least 70% of the panel. Results/Conclusions: Intralesional injectable corticotherapy was considered the first optionfor localized disease in adults. In extensive cases with signs of activity, systemic cortico-steroid therapy should be considered and can be used together with immunosuppressants (corticosteroid-sparing agents). The use of an immunosensitizer (diphencyprone) is an option for stable long-term cases. Evaluation of side effects is as important as the rate of hair regrowth. (C) 2020 Sociedade Brasileira de Dermatologia. Published by Elsevier Espana, S.L.U.
引用
收藏
页码:39 / 52
页数:14
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