Is there a SERT-ain association with IBS?

被引：38

作者：

Camilleri, M ^{[1
]}

机构：

[1] Mayo Clin & Mayo Fdn, CENTER, Rochester, MN 55905 USA

来源：

GUT | 2004年 / 53卷 / 10期

关键词：

D O I：

10.1136/gut.2004.039826

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The homozygous short genotype of SERT-P may be a candidate gene for diarrhoea predominant irritable bowel syndrome in women.

引用

页码：1396 / 1399

页数：4

共 30 条

[1] Platelet serotonin transporter in patients with diarrhea-predominant irritable bowel syndrome both before and after treatment with alosetron [J].

Bellini, M ;

Rappelli, L ;

Blandizzi, C ;

Costa, F ;

Stasi, C ;

Colucci, R ;

Giannaccini, G ;

Marazziti, D ;

Betti, L ;

Baroni, S ;

Mumolo, MG ;

Marchi, S ;

Del Tacca, M .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2003, 98 (12) :2705-2711

[2]

Belous AR, 1999, VOP MED KHIM, V45, P256

[3] Biogenic amine transporters: regulation in flux [J].

Blakely, RD ;

Bauman, AL .

CURRENT OPINION IN NEUROBIOLOGY, 2000, 10 (03) :328-336

[4] Physiological genomics of antidepressant targets: Keeping the periphery in mind [J].

Blakely, RD .

JOURNAL OF NEUROSCIENCE, 2001, 21 (21) :8319-8323

[5] Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome [J].

Camilleri, M ;

Atanasova, E ;

Carlson, PJ ;

Ahmad, U ;

Kim, HJ ;

Viramontes, BE ;

McKinzie, S ;

Urrutia, R .

GASTROENTEROLOGY, 2002, 123 (02) :425-432

[6] Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters [J].

Chen, JJ ;

Li, ZS ;

Pan, H ;

Murphy, DL ;

Tamir, H ;

Koepsell, H ;

Gershon, MD .

JOURNAL OF NEUROSCIENCE, 2001, 21 (16) :6348-6361

[7] Guinea pig 5-HT transporter: cloning, expression, distribution, and function in intestinal sensory reception [J].

Chen, JX ;

Pan, H ;

Rothman, TP ;

Wade, PR ;

Gershon, MD .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 1998, 275 (03) :G433-G448

[8] Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome [J].

Coates, MD ;

Mahoney, CR ;

Linden, DR ;

Sampson, JE ;

Chen, J ;

Blaszyk, H ;

Crowell, MD ;

Sharkey, KA ;

Gershon, MD ;

Mawe, GM ;

Moses, PL .

GASTROENTEROLOGY, 2004, 126 (07) :1657-1664

[9]

Gershon MD, 1999, ALIMENT PHARM THER, V13, P15

[10] Association between serotonin transporter gene polymorphism and anxiety-related traits [J].

Katsuragi, S ;

Kunugi, H ;

Sano, A ;

Tsutsumi, T ;

Isogawa, K ;

Nanko, S ;

Akiyoshi, J .

BIOLOGICAL PSYCHIATRY, 1999, 45 (03) :368-370

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