Synthesis, Herbicidal Activity, and Molecular Docking of New Pyrazole Ketone Derivatives Containing Flexible Chain

被引：0

作者：

Fu, Qing ^{[1
,2
]}

Guo, Chang-Fei ^{[1
,2
]}

Zhong, Liang-Kun ^{[1
,2
]}

Chen, Jie ^{[3
]}

Tan, Cheng-Xia ^{[1
]}

Weng, Jian-Quan ^{[1
]}

Xu, Tian-Ming ^{[2
]}

Liu, Xing-Hai ^{[1
]}

机构：

[1] Zhejiang Univ Technol, Coll Chem Engn, Dept Chem Technol, Hangzhou 310014, Peoples R China

[2] Zhejiang Res Inst Chem Ind, Zhejiang Base Natl Southern Pesticide Res Ctr, Hangzhou 310023, Peoples R China

[3] Zhejiang A&F Univ, Sch Forestry & Biotechnol, Dept Bot, Hangzhou 311300, Peoples R China

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2020年 / 30卷 / 03期

关键词：

Synthesis; Pyrazole ketone derivatives; 4-Hydoxyphenylpyruvate dioxygenase herbicides; Docking; Herbicidal activity; NEMATOCIDAL ACTIVITY; FUNGICIDAL ACTIVITY; CRYSTAL-STRUCTURE; CARBONATE DERIVATIVES; BIOLOGICAL-ACTIVITY; DESIGN; TRIKETONE; INHIBITORS; SAR;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of pyrazole derivatives was designed, synthesized, and characterized using prodrug theory. Compared with the commercial drug mesotrione, most of title compounds exhibited low herbicidal activity at 150 g/ha. The docking results showed that the binding mode of the key intermediate is the same as the reported inhibitor DAS689.

引用

页码：361 / 367

页数：7

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