Synthesis, Herbicidal Activity, and Molecular Docking of New Pyrazole Ketone Derivatives Containing Flexible Chain

被引：0
|
作者：
Fu, Qing [1 ,2 ]
Guo, Chang-Fei [1 ,2 ]
Zhong, Liang-Kun [1 ,2 ]
Chen, Jie [3 ]
Tan, Cheng-Xia [1 ]
Weng, Jian-Quan [1 ]
Xu, Tian-Ming [2 ]
Liu, Xing-Hai [1 ]
机构：
[1] Zhejiang Univ Technol, Coll Chem Engn, Dept Chem Technol, Hangzhou 310014, Peoples R China
[2] Zhejiang Res Inst Chem Ind, Zhejiang Base Natl Southern Pesticide Res Ctr, Hangzhou 310023, Peoples R China
[3] Zhejiang A&F Univ, Sch Forestry & Biotechnol, Dept Bot, Hangzhou 311300, Peoples R China
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2020年 / 30卷 / 03期
关键词：
Synthesis; Pyrazole ketone derivatives; 4-Hydoxyphenylpyruvate dioxygenase herbicides; Docking; Herbicidal activity; NEMATOCIDAL ACTIVITY; FUNGICIDAL ACTIVITY; CRYSTAL-STRUCTURE; CARBONATE DERIVATIVES; BIOLOGICAL-ACTIVITY; DESIGN; TRIKETONE; INHIBITORS; SAR;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of pyrazole derivatives was designed, synthesized, and characterized using prodrug theory. Compared with the commercial drug mesotrione, most of title compounds exhibited low herbicidal activity at 150 g/ha. The docking results showed that the binding mode of the key intermediate is the same as the reported inhibitor DAS689.
引用
收藏
页码：361 / 367
页数：7
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