Development and Validation of RP-HPLC Method for Estimation of Zolmitriptan in Tablet Dosage Forms

被引：0

作者：

Sankar, D. Gowri ^{[1
]}

Babu, A. Nagesh ^{[1
]}

Rajeswari, A. ^{[1
]}

Krishna, M. Vamsi ^{[1
]}

机构：

[1] Andhra Univ, Univ Coll Pharmaceut Sci, Dept Pharmaceut Anal & Qual Assurance, Visakhapatnam 530003, Andhra Pradesh, India

来源：

ASIAN JOURNAL OF CHEMISTRY | 2009年 / 21卷 / 07期

关键词：

Zolmitriptan; RP-HPLC; Tablets;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A rapid, simple and precise reversed phase high performance liquid chromatography (RP-HPLC) method was developed for the estimation of zolmitriptan in tablets. The quantification was carried out using a X-Terra RP C-18 column (150 mm x 4.6 mm i.d., 5 mu m particle size) in isocratic mode with mobile phase comprising of phosphate buffer, acetonitrile and methanol in the ratio of 65:15:20 (v/v) at a flow rate of 1 mL/min. The eluent was monitored at 225 nm. The retention time of the drug was 4.278 min. The calibration curve was linear in the concentration range of 5-70 mu g/mL and per cent recovery ranged from 99.8-100.08.

引用

页码：5019 / 5022

页数：4

共 50 条

[21] Development and Validation of Stability-indicating RP-HPLC Method for the Estimation of Pseudoephedrine, Ambroxol and Desloratadine in Bulk and Tablet Dosage Forms
Rao, N. Mallikarjuna
Sankar, D. Gowri
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2016, 78 (04) : 492 - 497
[22] Estimation of Levetiracetam in Tablet Dosage Form by RP-HPLC
Raju, N. Appala
Rao, J. Venkateswara
Prakash, K. Vanitha
Mukkanti, K.
Srinivasu, K.
E-JOURNAL OF CHEMISTRY, 2008, 5 : 1098 - 1102
[23] DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF THREE-COMPONENT IN TABLET DOSAGE FORMULATION
Joshi, Rupali S.
Katiyar, Sameer S.
Zope, Devendra B.
Shinde, Amol T.
ASIAN JOURNAL OF PHARMACEUTICAL RESEARCH AND HEALTH CARE, 2011, 3 (04) : 78 - 88
[24] DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR QUANTITATIVE ESTIMATION OF RITONAVIR IN BULK AND PHARMACEUTICAL DOSAGE FORMS
Chiranjeevi, K.
Channabasavaraj, K. P.
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2011, 2 (03): : 596 - 600
[25] DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR QUANTITATIVE ESTIMATION OF RITONAVIR IN BULK AND PHARMACEUTICAL DOSAGE FORMS
Chiranjeevi, K.
Channabasavaraj, K. P.
Lakshminarayana, B.
Kumar, B. Kalyan
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2011, 2 (02): : 336 - 340
[26] ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF PIOGLITAZONE AND GLIMEPIRIDE IN TABLET DOSAGE FORM BY RP-HPLC
Sharma, Ravi
Sharma, Gagan
Chopra, Darpan
Jain, Pavan Kumar
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2011, 2 (03): : 637 - 642
[27] Method Development and Validation for the Estimation of Dothiepin Hydrochloride by using RP-HPLC in PURE and Tablet Dosage Form
Thayi, Prasanthi
Atmakuri, Lakshman Rao
Mandada, Nandini
Mandava, Hemanth
Mandru, Bhuvaneswari
Manne, Chaitanya
INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH, 2019, 53 (02) : 310 - 315
[28] DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF AMLODIPINE BESYLATE AND INDAPAMIDE IN TABLET DOSAGE FORM
Raj, Manish C.
Chaudhari, Bharat G.
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2012, 3 (09): : 3146 - 3150
[29] DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF METFORMIN HYDROCHLORIDE AND REPAGLINIDE IN TABLET DOSAGE FORM
Soni, Love Kumar
Narsinghani, Tamanna
Jain, Madhavi
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2012, 35 (1-4) : 385 - 392
[30] Analytical method development and validation for the simultaneous estimation of lopinavir and ritonavir by RP-HPLC method in tablet dosage form
Anuradha, Akella
Aanandhi, M. Vijey
Patan, Afroz
ANNALS OF PHYTOMEDICINE-AN INTERNATIONAL JOURNAL, 2023, 12 (01): : 573 - 580

← 1 2 3 4 5 →