A facile synthesis of 2H-indazoles under neat conditions and further transformation into aza-γ-carboline alkaloid analogues in a tandem one-pot fashion

被引：38

作者：

Vidyacharan, Shinde ^{[1
]}

Sagar, A. ^{[1
]}

Chaitra, N. C. ^{[1
]}

Sharada, Duddu S. ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Yeddumailaram 502205, Telangana, India

来源：

RSC ADVANCES | 2014年 / 4卷 / 65期

关键词：

SOLID-PHASE SYNTHESIS; N BOND FORMATION; C-N; HETEROCYCLIC-COMPOUNDS; DOMINO REACTION; SOLVENT-FREE; INDAZOLES; DERIVATIVES; ACID; ISOCRYPTOLEPINE;

D O I：

10.1039/c4ra06838f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have described a facile, microwave-assisted, catalyst-free and solvent-free approach to 2H-indazoles and further developed a robust tandem one-pot metal-free strategy for C-C bond formation at the C-3 position of 2H-indazoles leading to a unique class of aza-gamma-carboline alkaloid analogues. This straightforward expedient synthesis constitutes an interesting alternative to the existing conventional transition metal catalyzed reactions.

引用

页码：34232 / 34236

页数：5

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