Both endometrial cancer and ovarian cancer can be part of Lynch syndrome/HNPCC. In this case patients also have an increased risk of developing colon cancer or cancer of other organs. Therefore, cancer screening can only be provided using an interdisciplinary clinical setting in these high-risk individuals and their families. Clinical aspects and the genetic background of Lynch syndrome/HNPCC are outlined. Screening recommendations as well as genetic counselling and testing are described in this review.
机构:
Mem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Moukarzel, L.
Paula, A. Da Cruz
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Mem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Paula, A. Da Cruz
Hoang, T.
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Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Hoang, T.
Sebastiao, A. P.
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Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Sebastiao, A. P.
Pareja, F.
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Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Pareja, F.
Park, K.
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Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Park, K.
Jungbluth, A.
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Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Jungbluth, A.
Capella, G.
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Catalonian Inst Oncol ICO IDIBELL, Hereditary Canc Unit, Barcelona, SpainMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Capella, G.
Pineda, M.
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Catalonian Inst Oncol ICO IDIBELL, Hereditary Canc Unit, Barcelona, SpainMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Pineda, M.
Reis-Filho, J.
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Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Reis-Filho, J.
Abu-Rustum, N.
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Mem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Abu-Rustum, N.
Levin, J.
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Mem Sloan Kettering Canc Ctr, Dept Med, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Levin, J.
Vidal Bel, A.
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Hosp Univ Bellvitge IDIBELL, Dept Pathol, Barcelona, SpainMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Vidal Bel, A.
Matias-Guiu, X.
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Hosp Univ Bellvitge IDIBELL, Dept Pathol, Barcelona, SpainMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Matias-Guiu, X.
Cadoo, K.
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Mem Sloan Kettering Canc Ctr, Dept Med, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Cadoo, K.
Stadler, Z.
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Mem Sloan Kettering Canc Ctr, Dept Med, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Stadler, Z.
Weigelt, B.
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Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Gynecol Serv, Dept Surg, 1275 York Ave, New York, NY 10021 USA
机构:
Univ Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77230 USAUniv Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77230 USA
Ready, Kaylene J.
Daniels, Molly S.
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Univ Texas MD Anderson Canc Ctr, Dept Gynecol Oncol, Unit 1362, Houston, TX 77230 USAUniv Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77230 USA
Daniels, Molly S.
Sun, Charlotte C.
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Univ Texas MD Anderson Canc Ctr, Dept Gynecol Oncol, Unit 1362, Houston, TX 77230 USAUniv Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77230 USA
Sun, Charlotte C.
Peterson, Susan K.
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Univ Texas MD Anderson Canc Ctr, Dept Behav Sci, Unit 1330, Houston, TX 77230 USAUniv Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77230 USA
Peterson, Susan K.
Northrup, Hope
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Univ Texas Houston, Houston Med Sch, Houston, TX USAUniv Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77230 USA
Northrup, Hope
Lu, Karen H.
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Univ Texas MD Anderson Canc Ctr, Dept Gynecol Oncol, Unit 1362, Houston, TX 77230 USAUniv Texas MD Anderson Canc Ctr, Dept Breast Med Oncol, Unit 1354, Houston, TX 77230 USA