Cationic Conjugated Polymers for Discrimination of Microbial Pathogens

被引：269

作者：

Yuan, Huanxiang ^{[1
]}

Liu, Zhang ^{[2
]}

Liu, Libing ^{[1
]}

Lv, Fengting ^{[1
]}

Wang, Yilin ^{[2
]}

Wang, Shu ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Chem, Key Lab Organ Solids Interface & Chem Thermodynam, Beijing 100190, Peoples R China

[2] Chinese Acad Sci, Key Lab Colloid Interface & Chem Thermodynam, Inst Chem, Beijing 100190, Peoples R China

来源：

ADVANCED MATERIALS | 2014年 / 26卷 / 25期

基金：

中国国家自然科学基金;

关键词：

BLOOD CULTURE BOTTLES; ISOTHERMAL TITRATION CALORIMETRY; ESCHERICHIA-COLI; CANDIDA-ALBICANS; GOLD-NANOPARTICLE; OPTICAL-DETECTION; BACTERIA; FLUORESCENT; DNA; POLYELECTROLYTES;

D O I：

10.1002/adma.201400636

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new cationic poly(phenylene vinylene) derivative (PPV-NMe3+) is synthesized, and it exhibits a differential binding ability to microbial cell walls with different components. By varying the ion strengths of the buffer solution, single PPV-NMe3+ molecules can discriminate fungi, Gram-positive bacteria, and Gram-negative bacteria in a rapid and simple manner. Thus, cationic conjugated polymers exhibit high potential as a diagnostic material for the detection and discrimination of pathogens.

引用

收藏

页码：4333 / 4338

页数：6

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