Bacillus coagulans BC198 and Lactobacillus paracasei S38 in combination reduce body fat accumulation and modulate gut microbiota

被引：4

作者：

Hsieh, Cheng-En ^{[1
]}

You, Fu-Nian ^{[1
]}

Dai, Fan-Jhen ^{[1
]}

Tung, Ying-Chia ^{[1
]}

Chen, Wei-Jen ^{[2
]}

Chu, Hui-Fang ^{[2
]}

Wu, Shiuan-Huei ^{[2
]}

Chau, Chi-Fai ^{[1
]}

机构：

[1] Natl Chung Hsing Univ, Dept Food Sci & Biotechnol, Taichung 40227, Taiwan

[2] Syngen Biotech Co Ltd, Dept Res & Dev, Tainan, Taiwan

来源：

CYTA-JOURNAL OF FOOD | 2020年 / 18卷 / 01期

关键词：

Bacillus coagulans BC198; Lactobacillus paracasei S38; body fat; microbiota; multi-strain; LIPID-METABOLISM; OBESITY;

D O I：

10.1080/19476337.2020.1843542

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Bacillus coagulans BC198 and Lactobacillus paracasei S38 in combination reduce body fat accumulation and modulate gut microbiota. This study investigated the effects of two single strains (Bacillus coagulans BC198 and Lactobacillus paracasei S38) at a level of 5 x 10(9) CFU and a mixture of these two strains (1 x 10(8) CFU) on body fat accumulation and gut microbiota in rats. In contrast to high-fat control, L. paracasei S38 intakes resulted in significant (p < .05) reductions in total visceral fat (-15%) and liver lipids (-19%). The supplementation of the multi-strain mixture at a relatively lower dose was more efficient (p < .05) in reducing feed efficiency (-17%), total visceral fat (-30%), and liver lipids (-32%). A higher concentration of total short-chain fatty acids and a higher proportion of Bacteroidetes were also observed in the fecal samples of the multi-strain group. Consumption of multiple strains of B. coagulans BC198 and L. paracasei S38 appeared to show greater efficacy than single strains even at a relatively low dose.

引用

页码：764 / 775

页数：12

共 39 条

[31] Small Intestine Microbiota Regulate Host Digestive and Absorptive Adaptive Responses to Dietary Lipids [J].

Martinez-Guryn, Kristina ;

Hubert, Nathaniel ;

Frazier, Katya ;

Urlass, Saskia ;

Musch, Mark W. ;

Ojeda, Patricia ;

Pierre, Joseph F. ;

Miyoshi, Jun ;

Sontag, Timothy J. ;

Cham, Candace M. ;

Reardon, Catherine A. ;

Leone, Vanessa ;

Chang, Eugene B. .

CELL HOST & MICROBE, 2018, 23 (04) :458-+

[32] The gut microbiome in health and in disease [J].

Shreiner, Andrew B. ;

Kao, John Y. ;

Young, Vincent B. .

CURRENT OPINION IN GASTROENTEROLOGY, 2015, 31 (01) :69-75

[33] High-fat diet-induced obesity is attenuated by probiotic strain Lactobacillus paracasei ST11 (NCC2461) in rats [J].

Tanida, Mamoru ;

Shen, Jiao ;

Maeda, Keiko ;

Horii, Yuko ;

Yamano, Toshihiko ;

Fukushima, Yoichi ;

Nagai, Katsuya .

OBESITY RESEARCH & CLINICAL PRACTICE, 2008, 2 (03) :159-169

[34] Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome composition [J].

Wong, M-L ;

Inserra, A. ;

Lewis, M. D. ;

Mastronardi, C. A. ;

Leong, L. ;

Choo, J. ;

Kentish, S. ;

Xie, P. ;

Morrison, M. ;

Wesselingh, S. L. ;

Rogers, G. B. ;

Licinio, J. .

MOLECULAR PSYCHIATRY, 2016, 21 (06) :797-805

[35] Function of Akkermansia muciniphila in Obesity: Interactions With Lipid Metabolism, Immune Response and Gut Systems [J].

Xu, Yu ;

Wang, Ning ;

Tan, Hor-Yue ;

Li, Sha ;

Zhang, Cheng ;

Feng, Yibin .

FRONTIERS IN MICROBIOLOGY, 2020, 11

[36] Beneficial Metabolic Effects of a Probiotic via Butyrate-induced GLP-1 Hormone Secretion [J].

Yadav, Hariom ;

Lee, Ji-Hyeon ;

Lloyd, John ;

Walter, Peter ;

Rane, Sushil G. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 288 (35) :25088-25097

[37] Probiotics L. plantarum and L. curvatus in Combination Alter Hepatic Lipid Metabolism and Suppress Diet-Induced Obesity [J].

Yoo, Sae-Rom ;

Kim, Young-Jae ;

Park, Do-Young ;

Jung, Un-Ju ;

Jeon, Seon-Min ;

Ahn, Young-Tae ;

Huh, Chul-Sung ;

McGregor, Robin ;

Choi, Myung Sook .

OBESITY, 2013, 21 (12) :2571-2578

[38] Discrepant gut microbiota markers for the classification of obesity-related metabolic abnormalities [J].

Zeng, Qiang ;

Li, Dongfang ;

He, Yuan ;

Li, Yinhu ;

Yang, Zhenyu ;

Zhao, Xiaolan ;

Liu, Yanhong ;

Wang, Yu ;

Sun, Jing ;

Feng, Xin ;

Wang, Fei ;

Chen, Jiaxing ;

Zheng, Yuejie ;

Yang, Yonghong ;

Sun, Xuelin ;

Xu, Ximing ;

Wang, Daxi ;

Kenney, Toby ;

Jiang, Yiqi ;

Gu, Hong ;

Li, Yongli ;

Zhou, Ke ;

Li, Shuaicheng ;

Dai, Wenkui .

SCIENTIFIC REPORTS, 2019, 9 (1)

[39] Dietary corn-resistant starch suppresses broiler abdominal fat deposition associated with the reduced cecal Firmicutes [J].

Zhang, Yingying ;

Liu, Yingsen ;

Li, Jiaolong ;

Xing, Tong ;

Jiang, Yun ;

Zhang, Lin ;

Gao, Feng .

POULTRY SCIENCE, 2020, 99 (11) :5827-5837

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