Characteristics and risk factors for early-onset metachronous colorectal adenoma

被引:5
作者
Sardo Molmenti, Christine L. [1 ,2 ]
Hibler, Elizabeth A. [3 ]
Yang, Jingyan [4 ]
Kolb, Jennifer M. [5 ]
Yang, Jane [6 ]
Hussain, Maryam [2 ]
Andersen, Shaneda Warren [7 ]
Shivappa, Nitin [8 ,9 ,10 ]
Hebert, James R. [8 ,9 ,10 ]
Lance, Peter [11 ]
Alberts, David S. [12 ,13 ]
Neugut, Alfred, I [4 ,14 ,15 ]
Jacobs, Elizabeth T. [12 ,13 ]
机构
[1] Donald & Barbara Zucker Sch Med Hofstra Northwell, Dept Occupat Med Epidemiol & Prevent, Hempstead, NY 11549 USA
[2] Feinstein Inst Med Res, Manhasset, NY 11030 USA
[3] Northwestern Univ, Feinberg Sch Med, Div Epidemiol, Chicago, IL 60611 USA
[4] Columbia Univ, Mailman Sch Publ Hlth, New York, NY 10032 USA
[5] Univ Colorado Anschutz Med Campus, Div Gastroenterol & Hepatol, Aurora, CO 80045 USA
[6] Northwell Hlth, Dept Surg, Manhasset, NY 10032 USA
[7] Univ Wisconsin, Dept Populat Hlth Sci, Sch Med & Publ Hlth, Madison, WI 53726 USA
[8] Univ South Carolina, Arnold Sch Publ Hlth, Dept Epidemiol & Biostat, Columbia, SC 29208 USA
[9] Univ South Carolina, Arnold Sch Publ Hlth, Canc Prevent & Control Program, Columbia, SC 29208 USA
[10] Connecting Hlth Innovat LLC, Columbia, SC 29201 USA
[11] Univ Arizona, Dept Mol & Cellular Biol, Tucson, AZ 85721 USA
[12] Univ Arizona, Mel & Enid Zuckerman Coll Publ Hlth, Tucson, AZ 85724 USA
[13] Univ Arizona, Comprehens Canc Ctr, Tucson, AZ 85724 USA
[14] Columbia Univ, Vagelos Coll Phys & Surg, Herbert Irving Comprehens Canc Ctr, New York, NY 10032 USA
[15] Columbia Univ, Vagelos Coll Phys & Surg, Med Ctr, Dept Med, New York, NY 10032 USA
关键词
colorectal adenoma; colorectal adenoma recurrence; colorectal cancer; early-onset colorectal cancer; metachronous colorectal adenoma; risk factors; OCCUPATIONAL PHYSICAL-ACTIVITY; SOCIETY TASK-FORCE; NIH-AARP DIET; COLON-CANCER; FREQUENCY QUESTIONNAIRE; SEDENTARY BEHAVIOR; CIGARETTE-SMOKING; UNITED-STATES; YOUNG-ADULTS; OLDER-ADULTS;
D O I
10.2217/crc-2020-0019
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Aim: Compare risk factors for early-onset-metachronous colorectal adenoma (EOMCA) among individuals Materials & methods: Descriptive statistics compared clinical/demographic characteristics for individuals Results: N = A total of 1623 participants. Individuals <50 years (vs >= 50) had higher smoking rates, greater intake of red meat, monounsaturated fatty acids, total fat and less sleep, sedentary behavior, aspirin intake, supplemental calcium use and higher mean energy-adjusted dietary inflammatory index (E-DII) score (pro-inflammatory diet) (all p <= 0.001). Odds of EOMCA were higher among smokers and participants reporting previous polyp(s). Overall odds of EOMCA were lower among individuals <= 50. Conclusion: History of previous polyps and smoking were risk factors for EOMCA. Lifestyle factors require further research.
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收藏
页数:13
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