Synthesis of Some 4′-Amino Chalcones and their Antiinflammatory and Antimicrobial Activity

被引：0

作者：

Prasad, Y. Rajendra ^{[1
]}

Rao, A. Srinivasa ^{[1
]}

Rambabu, R. ^{[1
]}

机构：

[1] Andhra Univ, AU Coll Pharmaceut Sci, Pharmaceut Chem Div, Visakhapatnam 530003, Andhra Pradesh, India

来源：

ASIAN JOURNAL OF CHEMISTRY | 2009年 / 21卷 / 02期

关键词：

Chalcone; Synthesis; Antiinflammatory; Antimicrobial activity; EDEMA; PAW;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of some 4'-amino chalcones were synthesized by Claisen-Schmidt condensation of 4-amino acetophenone with various substituted aromatic aldehydes. The synthesized chalcones were characterized by IR, H-1 NMR and elemental analyses. When these chalcones (3a-h) were evaluated for anti inflammatory, antibacterial and antifungal activities, some of them found to possess significant biological activity when compared to standard drugs.

引用

页码：907 / 914

页数：8

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