Management of Patients With ST- Segment Elevation or Non- ST- Segment Elevation Acute Coronary Syndromes in Cardiac Rehabilitation Centers

被引:14
作者
Reibis, Rona [1 ,2 ]
Voeller, Heinz [1 ,3 ]
Gitt, Anselm [4 ]
Jannowitz, Christina [5 ]
Halle, Martin [6 ]
Pittrow, David [7 ]
Hildemann, Steven [8 ,9 ]
机构
[1] Klin See, Dept Cardiol, Rudersdorf, Germany
[2] Pk Sanssouci, Cardiol Outpatient Clin, Potsdam, Germany
[3] Univ Potsdam, Rehabil Res Ctr, D-14469 Potsdam, Germany
[4] Inst Heart Attack Res, Ludwigshafen, Germany
[5] MSD Sharp & Dohme GmbH, Med Affairs, Haar, Germany
[6] Tech Univ Munich, Dept Med, Div Prevent Rehabil & Sports Med, Univ Hosp, D-80290 Munich, Germany
[7] Tech Univ Dresden, Inst Clin Pharmacol, D-01062 Dresden, Germany
[8] Merck Res Labs MSD MRL, Haar, Germany
[9] Univ Heart Ctr, Univ Clin Cardiol & Angiol 1, Freiburg, Germany
关键词
ACUTE MYOCARDIAL-INFARCTION; SECONDARY PREVENTION; RISK; INTERVENTION; EZETIMIBE; EFFICACY; REGISTRY; METAANALYSIS; SIMVASTATIN; GUIDELINES;
D O I
10.1002/clc.22241
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BackgroundCurrent data on the management of patients in cardiac rehabilitation (CR) after an acute hospital stay due to ST-segment elevation or non-ST segment elevation acute coronary syndromes (STE-ACS or NSTE-ACS) are limited. We aimed to describe patient characteristics, risk factor management, and lipid target achievement of patients in CR in Germany and compare the 2 groups. HypothesisWith respect to the risk factor pattern and treatment effects during a CR stay, there are important differences between STE-ACS and NSTE-ACS patients. MethodsComparison of 7950 patients by STE-ACS or NSTE-ACS status in the Transparency Registry to Objectify Guideline-Oriented Risk Factor Management registry (2010) who underwent an inpatient CR period of about 3 weeks. ResultsSTE-ACS patients compared to NSTE-ACS patients were significantly younger (60.5 vs 64.4 years, P < 0.0001), and had diabetes mellitus, hypertension, or any risk factor (exception: smoking) less often. At discharge, in STE-ACS compared to NSTE-ACS patients, the low-density lipoprotein cholesterol (LDL-C) <100 mg/dL goal was achieved by 75.3% and 76.2%, respectively (LDL-C <70 mg/dL by 27.7% and 27.4%), the high-density lipoprotein cholesterol goal of >50 mg/dL in women and >40 mg/dL in men was achieved by 49.3% and 49.0%, respectively, and the triglycerides goal of <150 mg/dl was achievedby 72.3% and 74.3%, respectively (all comparisons not significant). Mean systolic and diastolic blood pressure were 121/74 and 123/74 mm Hg, respectively (P < 0.0001 systolic, diastolic not significant). The maximum exercise capacity was 110 and 102 W, respectively (P < 0.0001), and the maximum walking distance was 581 and 451 meters, respectively (P value not significant). ConclusionsPatients with STE-ACS and NSTE-ACS differed moderately in their baseline characteristics. Both groups benefited from the participation in CR, as their lipid profile, blood pressure, and physical fitness improved.
引用
收藏
页码:213 / 221
页数:9
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