Post-transplant multiple myeloma in a pediatric renal transplant patient

被引：27

作者：

Tcheng, WY

Said, J

Hall, T

Al-Akash, S

Malogolowkin, M

Feig, SA

机构：

[1] Univ Calif Los Angeles, Gwynne Hazen Cherry Mem Labs, Div Pediat Hematol Oncol, Los Angeles, CA USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Pathol, Los Angeles, CA USA

[3] Univ Calif Los Angeles, David Geffen Sch Med, Dept Radiol, Los Angeles, CA USA

[4] Univ Calif Los Angeles, Mattel Childrens Hosp, Div Nephrol, Dept Pediat, Los Angeles, CA USA

[5] Keck USC Sch Med, Childrens Hosp Los Angeles, Div Hematol Oncol, Los Angeles, CA USA

来源：

PEDIATRIC BLOOD & CANCER | 2006年 / 47卷 / 02期

关键词：

Epstein-Barr virus; multiple myeloma; post-transplant lymphoproliferative disease;

D O I：

10.1002/pbc.20482

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Post-transplant lymphoproliferative disease (PTLD) is a well-recognized complication of the intense immunosuppression required in solid organ and bone marrow transplant recipients. The clinical presentation is varied and can range from a benign infectious mononucleosis-like syndrome to malignant lymphoma. PTLD manifesting as multiple myeloma occurs rarely. We report the unique occurrence of Epstein-Barr virus (EBV)-associated post-transplant multiple myeloma in a 16-year-old male. In contrast to previously described cases of PTLD-myeloma type, this patient was very young, had a clear association with EBV, and an indolent clinical course.

引用

页码：218 / 223

页数：6

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