Reporting bias in retrospective ascertainment of drug-induced embryopathy

被引：47

作者：

Bar-Oz, B

Moretti, ME

Mareels, G

Van Tittelboom, T

Koren, G

机构：

[1] Hosp Sick Children, Div Clin Pharmacol, Motherisk Program, Toronto, ON M5G 1X8, Canada

[2] Univ Toronto, Chair Child Hlth Res, CIBC Wood Gundy Childrens Miracle Fdn, Toronto, ON, Canada

[3] Janssen Pharmaceut, B-2340 Beerse, Belgium

来源：

LANCET | 1999年 / 354卷 / 9191期

关键词：

D O I：

10.1016/S0140-6736(99)04411-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The rate of congenital malformations after first-trimester exposure to itraconazole was four times higher when ascertained retrospectively than prospectively (13.0 vs 3.2%, p = 0.006). Reporting bias in retrospective studies should be acknowledged in interpretation of such data.

引用

页码：1700 / 1701

页数：2

共 4 条

[1] PERCEPTION OF TERATOGENIC RISK BY PREGNANT-WOMEN EXPOSED TO DRUGS AND CHEMICALS DURING THE 1ST TRIMESTER [J].