The role of Toll-like receptors in immunity against mycobacterial infection

被引：130
作者：
Heldwein, KA [1 ]
Fenton, MJ [1 ]
机构：
[1] Boston Univ, Sch Med, Ctr Pulm, Boston, MA 02118 USA
来源：
MICROBES AND INFECTION | 2002年 / 4卷 / 09期
关键词：
tuberculosis; macrophages; Toll-like receptors;
D O I：
10.1016/S1286-4579(02)01611-8
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Recent work implicates Toll-like receptor (TLR) proteins as regulators of innate immune cell activation induced by Mycobacterium tuberculosis, which continues to ravage nearly one-third of the world's population. Novel insights into how TLR proteins may dictate the nature and extent of cellular immune responses against this pathogen will be discussed. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码：937 / 944
页数：8
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