Prepackaged Ramberg-Backlund reagents: useful tools for organic synthesis

被引：11
作者：
Block, E [1 ]
Jeon, HR [1 ]
Putman, D [1 ]
Zhang, SZ [1 ]
机构：
[1] SUNY Albany, Dept Chem, Albany, NY 12222 USA
来源：
TETRAHEDRON | 2004年 / 60卷 / 35期
基金：
美国国家科学基金会;
关键词：
Ramberg-Backlund reaction; alpha-halosulfones;
D O I：
10.1016/j.tet.2004.06.032
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis and reactions of several mu,beta-unsaturated chloromethyl sulfones is presented, for example [(chloromethyl)-sulfonyl]-1,3-propadiene (4), [(chloromethyl)sulfonyl]ethene (5), [(dichloromethyl)sulfonyl]ethene (6) and (E,Z)-1,2-bis[(chloromethyl)-sulfonyl]ethene (7). These compounds serve as 'prepackaged' Ramberg-Backlund reagents, which following an appropriate first step, such as Diels-Alder addition, react with base giving Ramberg-Backlund products. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：7525 / 7541
页数：17
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