A ROMPGEL-supported N-hydroxysuccinimide:: A host of acylations with minimal purification

被引：45
作者：
Barrett, AGM [1 ]
Cramp, SM
Roberts, RS
Zecri, FJ
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England
[2] Rhone Poulenc Agr Ltd, Ongar CM5 0HW, Essex, England
来源：
ORGANIC LETTERS | 2000年 / 2卷 / 03期
关键词：
D O I：
10.1021/ol991208w
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] A novel N-hydroxysuccinimide ring-opening metathesis polymer is described as a recyclable supported acyl transfer reagent. Amides, carbamates, ureas, Weinreb amides, and hydroxamic acids are all obtained in excellent yields and purities from amines with minimal purification.
引用
收藏
页码：261 / 264
页数：4
相关论文
共 45 条
  • [1] Resin-supported labeling reagents
    Adamczyk, M
    Fishpaugh, JR
    Mattingly, PG
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (02) : 217 - 220
  • [2] Preparation and use of N-hydroxysuccinimidyl active ester resins
    Adamczyk, M
    Fishpaugh, JR
    Mattingly, PG
    [J]. TETRAHEDRON LETTERS, 1999, 40 (03) : 463 - 466
  • [3] SYNTHESES AND REACTIONS OF FUNCTIONAL POLYMERS .42. PREPARATION AND USE OF POLYMERS HAVING N-HYDROXY-SUCCINIMIDE UNIT IN CHAIN
    AKIYAMA, M
    NARITA, M
    OKAWARA, M
    [J]. JOURNAL OF POLYMER SCIENCE PART A-1-POLYMER CHEMISTRY, 1969, 7 (5PA1): : 1299 - &
  • [4] SYNTHESES AND REACTIONS OF FUNCTIONAL POLYMERS .46. PREPARATION AND REACTIONS OF N-BENZYLOXYISOMALEIMIDE-STYRENE COPOLYMER
    AKIYAMA, M
    YANAGISA.Y
    OKAWARA, M
    [J]. JOURNAL OF POLYMER SCIENCE PART A-1-POLYMER CHEMISTRY, 1969, 7 (7PA1): : 1905 - &
  • [5] AKIYAMA M, 1976, TETRAHEDRON LETT, P1015
  • [6] USE OF RESINS CONTAINING MIXED SULFONIC-ACETIC ANHYDRIDES AS ACYLATING AGENTS
    ANG, TL
    HARWOOD, HJ
    [J]. JOURNAL OF MACROMOLECULAR SCIENCE-CHEMISTRY, 1973, A 7 (05): : 1079 - 1083
  • [7] Multi-valent polymer of vancomycin: enhanced antibacterial activity against VRE
    Arimoto, H
    Nishimura, K
    Kinumi, T
    Hayakawa, I
    Uemura, D
    [J]. CHEMICAL COMMUNICATIONS, 1999, (15) : 1361 - 1362
  • [8] Horner-Emmons synthesis with minimal purification using ROMPGEL: A novel high-loading matrix for supported reagents
    Barrett, AGM
    Cramp, SM
    Roberts, RS
    Zecri, FJ
    [J]. ORGANIC LETTERS, 1999, 1 (04) : 579 - 582
  • [9] ROMP-spheres: A novel high-loading polymer support using cross metathesis between vinyl polystyrene and norbornene derivatives
    Barrett, AGM
    Cramp, SM
    Roberts, RS
    [J]. ORGANIC LETTERS, 1999, 1 (07) : 1083 - 1086
  • [10] Synthesis of catalytically active polymers by means of ROMP:: An effective approach toward polymeric homogeneously soluble catalysts
    Bolm, C
    Dinter, CL
    Seger, A
    Höcker, H
    Brozio, J
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (16) : 5730 - 5731
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