Neuromodulation Options and Patient Selection for Parkinson's Disease

被引：5

作者：

Rajan, Roopa ^{[1
]}

Skorvanek, Matej ^{[2
,3
]}

Magocova, Veronika ^{[2
,3
]}

Siddiqui, Junaid ^{[4
]}

AlSinaidi, Omar A. ^{[5
]}

Shinawi, Heba M. ^{[5
]}

AlSubaie, Fahd ^{[6
]}

AlOmar, Najeeb ^{[6
]}

Deogaonkar, Milind ^{[7
]}

Bajwa, Jawad A. ^{[5
]}

机构：

[1] All India Inst Med Sci, Dept Neurol, New Delhi, India

[2] Safarik Univ, Dept Neurol, Kosice, Slovakia

[3] Univ Hosp L Pasteur, Dept Neurol, Kosice, Slovakia

[4] Univ Missouri, Sch Med, Dept Neurol, Columbia, MO USA

[5] King Fahad Med City, Natl Neurosci Inst, Dept Neurol, Riyadh 12231, Saudi Arabia

[6] King Fahad Med City, Natl Neurosci Inst, Dept Neurosurg, Riyadh, Saudi Arabia

[7] West Virginia Univ, Dept Neurol Surg, Morgantown, WV 26506 USA

来源：

NEUROLOGY INDIA | 2020年 / 68卷

关键词：

Parkinson's disease; neuromodulation; deep brain stimulation; infusion therapies; lesioning; SPINAL-CORD STIMULATION; DEEP-BRAIN-STIMULATION; TRANSCRANIAL MAGNETIC STIMULATION; LEVODOPA-INDUCED DYSKINESIAS; CARBIDOPA INTESTINAL GEL; SUBTHALAMIC STIMULATION; RANDOMIZED-TRIAL; MOTOR CORTEX; APOMORPHINE; INFUSION;

D O I：

10.4103/0028-3886.302473

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Neuromodulation therapies, including deep brain stimulation (DBS) and pump therapies, are currently the standard of care for PD patients with advanced disease and motor complications that are difficult to control with medical management alone. The quest for alternate lesser invasive approaches led to the development of several novel therapies like intrajejunal levodopa infusions (IJLI), continuous subcutaneous apomorphine infusions (CSAI) and Magnetic Resonance guided Focused Ultrasound (MRgFUS) in recent years. To achieve good outcomes with any of these therapeutic modalities, careful patient selection, multidisciplinary evaluation and technical expertise are equally important. In this review, we will provide an overview of the neuromodulation strategies currently available for PD, emphasizing on patient selection and choosing among the various strategies.

引用

页码：170 / 178

页数：9

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