Radionuclide-Activated Nanomaterials and Their Biomedical Applications

被引:49
作者
Ferreira, Carolina A. [1 ,2 ,3 ]
Ni, Dalong [1 ,2 ,3 ]
Rosenkrans, Zachary T. [1 ,2 ,3 ]
Cai, Weibo [1 ,2 ,3 ]
机构
[1] Univ Wisconsin, Dept Radiol, Madison, WI 53705 USA
[2] Univ Wisconsin, Dept Biomed Engn, Madison, WI 53705 USA
[3] Univ Wisconsin, Dept Med Phys, Madison, WI 53705 USA
基金
美国国家卫生研究院;
关键词
Cerenkov radiation; nanomedicine; radioactivation; radionuclides; theranostics; POSITRON-EMISSION-TOMOGRAPHY; RADIATION ENERGY-TRANSFER; CERENKOV LUMINESCENCE; QUANTUM DOTS; GOLD NANOPARTICLES; IN-VITRO; CHERENKOV RADIATION; CANCER-CELLS; TUMOR UPTAKE; THERAPY;
D O I
10.1002/anie.201900594
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Radio-nanomedicine, or the use of radiolabeled nanoparticles in nuclear medicine, has attracted much attention in the last few decades. Since the discovery of Cerenkov radiation and its employment in Cerenkov luminescence imaging, the combination of nanomaterials and Cerenkov radiation emitters has been revolutionizing the way nanomaterials are perceived in the field: from simple inert carriers of radioactivity to activatable nanomaterials for both diagnostic and therapeutic applications. Herein, we provide a comprehensive review on the types of nanomaterials that have been used to interact with Cerenkov radiation and the gamma and beta scintillation of radionuclides, as well as on their biological applications.
引用
收藏
页码:13232 / 13252
页数:21
相关论文
共 99 条
  • [1] The potential for Cerenkov luminescence imaging of alpha-emitting radionuclides
    Ackerman, N. L.
    Graves, E. E.
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2012, 57 (03) : 771 - 783
  • [2] Andreescu S., 2012, FINE PARTICLES MED P, P57, DOI DOI 10.1007/978-1-4614-0379-1_3
  • [3] [Anonymous], 2012, ANGEW CHEM, DOI DOI 10.1002/ANGE.201203031
  • [4] Quantitative Modeling of Cerenkov Light Production Efficiency from Medical Radionuclides
    Beattie, Bradley J.
    Thorek, Daniel L. J.
    Schmidtlein, Charles R.
    Pentlow, Keith S.
    Humm, John L.
    Hielscher, Andreas H.
    [J]. PLOS ONE, 2012, 7 (02):
  • [5] Redshifted Cherenkov Radiation for in vivo Imaging: Coupling Cherenkov Radiation Energy Transfer to multiple Forster Resonance Energy Transfers
    Bernhard, Yann
    Collin, Bertrand
    Decreau, Richard A.
    [J]. SCIENTIFIC REPORTS, 2017, 7
  • [6] Inter/intramolecular Cherenkov radiation energy transfer (CRET) from a fluorophore with a built-in radionuclide
    Bernhard, Yann
    Collin, Bertrand
    Decreau, Richard A.
    [J]. CHEMICAL COMMUNICATIONS, 2014, 50 (51) : 6711 - 6713
  • [7] In vivo fate tracking of degradable nanoparticles for lung gene transfer using PET and Cerenkov imaging
    Black, Kvar C. L.
    Ibricevic, Aida
    Gunsten, Sean P.
    Flores, Jeniree A.
    Gustafson, Tiffany P.
    Raymond, Jeffery E.
    Samarajeewa, Sandani
    Shrestha, Ritu
    Felder, Simcha E.
    Cai, Tianyi
    Shen, Yuefei
    Lobs, Ann-Kathrin
    Zhegalova, Natalia
    Sultan, Deborah H.
    Berezin, Mikhail
    Wooley, Karen L.
    Liu, Yongjian
    Brody, Steven L.
    [J]. BIOMATERIALS, 2016, 98 : 53 - 63
  • [8] Radioactive 198Au-Doped Nanostructures with Different Shapes for In Vivo Analyses of Their Biodistribution, Tumor Uptake, and Intratumoral Distribution
    Black, Kvar C. L.
    Wang, Yucai
    Luehmann, Hannah P.
    Cai, Xin
    Xing, Wenxin
    Pang, Bo
    Zhao, Yongfeng
    Cutler, Cathy S.
    Wang, Lihong V.
    Liu, Yongjian
    Xia, Younan
    [J]. ACS NANO, 2014, 8 (05) : 4385 - 4394
  • [9] SCINTILLATOR MATERIALS
    BLASSE, G
    [J]. CHEMISTRY OF MATERIALS, 1994, 6 (09) : 1465 - 1475
  • [10] Stimuli-Responsive Nanomaterials for Biomedical Applications
    Blum, Angela P.
    Kammeyer, Jacquelin K.
    Rush, Anthony M.
    Callmann, Cassandra E.
    Hahn, Michael E.
    Gianneschi, Nathan C.
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015, 137 (06) : 2140 - 2154