Febrile seizures: Current understanding of pathophysiological mechanisms

被引：16
作者：
Auvin, S. [1 ,2 ,3 ]
Vallee, L. [2 ,3 ]
机构：
[1] Hop Robert Debre, AP HP, Serv Neurol Pediat & Malad Metab, F-75019 Paris, France
[2] CHRU Lille, Serv Neurol Pediat, F-59037 Lille, France
[3] Fac Med Lille, Pharmacol Lab, EA 1046, F-59045 Lille, France
来源：
ARCHIVES DE PEDIATRIE | 2009年 / 16卷 / 05期
关键词：
HUMAN HERPESVIRUS-6 INFECTION; CENTRAL-NERVOUS-SYSTEM; INFLUENZA-A; CONVULSIONS; CHILDREN; HYPERTHERMIA; EPILEPSY; VIRUSES; IDENTIFICATION; ASSOCIATION;
D O I：
10.1016/j.arcped.2009.02.001
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Febrile seizures (FS) are the most common etiology of seizure in infants and children. The pathophysiological mechanisms are not clearly understood. We review the current factors that are thought to be involved in FS occurrence. Genetic factors, a fever component (immune response to infection and rise in body temperature), and neurotopic viruses are discussed. There are currently no data supporting the notion that a rapid rise in temperature provokes FS. Regarding the available data, it is obvious that several factors act together to induce FS. (c) 2009 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：450 / 456
页数：7
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