Tolerance induction in hypersensitivity reactions from drugs: a brief overview

被引:0
作者
Bircher, Andreas J. [1 ]
Hofmeier, Katrin Scherer [1 ]
机构
[1] Univ Basel Hosp, Allergy Unit, Dermatol Clin, CH-4031 Basel, Switzerland
关键词
desensitization; drug hypersensitivity; tolerance induction; HUMAN-IMMUNODEFICIENCY-VIRUS; BETA-LACTAM ANTIBIOTICS; RAPID DESENSITIZATION; TRIMETHOPRIM-SULFAMETHOXAZOLE; CYSTIC-FIBROSIS; INTRAVENOUS DESENSITIZATION; INFECTED PATIENTS; AIDS PATIENTS; ALLERGY; PATIENT;
D O I
10.1684/ejd.2013.2254
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Drug hypersensitivity reactions can occur with many drugs, are unpredictable, may affect any organ system and range widely in clinical severity from mild pruritus to exanthems to anaphylaxis. In most cases, the suspected drug must be avoided in the future. However, for certain patients, the particular drug may be essential for an optimal therapy. Under these circumstances, desensitization may be performed.
引用
收藏
页码:154 / 157
页数:4
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