The effects of osmotic and hydrostatic pressures on macromolecular systems

被引:53
作者
Kornblatt, JA [1 ]
Kornblatt, MJ [1 ]
机构
[1] Concordia Univ, Dept Biol, Enzyme Res Grp, Montreal, PQ H3G 1M8, Canada
来源
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY | 2002年 / 1595卷 / 1-2期
基金
加拿大自然科学与工程研究理事会;
关键词
protein hydration; hydrostatic pressure; osmotic pressure;
D O I
10.1016/S0167-4838(01)00333-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Osmotic pressure and hydrostatic pressure can be used effectively to probe the behavior of biologically important macromolecules and their complexes. Using the two techniques requires a theoretical framework as well as knowledge of the more common pitfalls. Both are discussed in this review in the context of several examples. (C) 2002 Elsevier Science B.V. All fights reserved.
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页码:30 / 47
页数:18
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