Ultrastructural features and ICSI treatment of severe teratozoospermia: report of two human cases of globozoospermia

被引：22

作者：

Nardo, LG

Sinatra, F

Bartoloni, G

Zafarana, S

Nardo, F ^{[1
]}

机构：

[1] Univ Catania, Ctr Reprod Med & Infertil, Dept Obstet & Gynaecol & Radiol Sci, Ascoli Tomaselli Hosp, I-95125 Catania, Italy

[2] Univ Catania, Dept Biomed Sci, I-95125 Catania, Italy

[3] Univ Catania, Dept Pathol, Ascoli Tomaselli Hosp, I-95125 Catania, Italy

来源：

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 2002年 / 104卷 / 01期

关键词：

globozoospermia; ICSL; karyotype; pregnancy outcomes; SEM; TEM;

D O I：

10.1016/S0301-2115(01)00602-9

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Abnormal sperm morphology is associated with male infertility. We describe two human cases of globozoospermia (round-headed spermatozoa) together with fine diagnosis and proposed treatment. Scanning and transmission electron microscopy (SEM and TEM) were performed to identify the ultrastructural features. Female partners underwent ovarian hyperstimulation and intracytoplasmic sperm injection (ICSI). Fertilized oocytes were transferred 36 h later. One couple had a healthy live-birth. Ultrastructural analysis may help to diagnose sperm morphology and identify those which will respond to treatment. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：40 / 42

页数：3

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