共 89 条
Contribution of Maternal Immunity to Decreased Rotavirus Vaccine Performance in Low- and Middle-Income Countries
被引:30
作者:

Mwila, Katayi
论文数: 0 引用数: 0
h-index: 0
机构:
Ctr Infect Dis Res Zambia, Lusaka, Zambia Ctr Infect Dis Res Zambia, Lusaka, Zambia

Chilengi, Roma
论文数: 0 引用数: 0
h-index: 0
机构:
Ctr Infect Dis Res Zambia, Lusaka, Zambia
Univ N Carolina, Sch Med, Dept Family Med, Chapel Hill, NC USA Ctr Infect Dis Res Zambia, Lusaka, Zambia

Simuyandi, Michelo
论文数: 0 引用数: 0
h-index: 0
机构:
Ctr Infect Dis Res Zambia, Lusaka, Zambia Ctr Infect Dis Res Zambia, Lusaka, Zambia

Permar, Sallie R.
论文数: 0 引用数: 0
h-index: 0
机构:
Duke Univ, Dept Pediat, Human Vaccine Inst, Durham, NC 27706 USA Ctr Infect Dis Res Zambia, Lusaka, Zambia

Becker-Dreps, Sylvia
论文数: 0 引用数: 0
h-index: 0
机构:
Univ N Carolina, Sch Med, Dept Family Med, Chapel Hill, NC USA Ctr Infect Dis Res Zambia, Lusaka, Zambia
机构:
[1] Ctr Infect Dis Res Zambia, Lusaka, Zambia
[2] Duke Univ, Dept Pediat, Human Vaccine Inst, Durham, NC 27706 USA
[3] Univ N Carolina, Sch Med, Dept Family Med, Chapel Hill, NC USA
关键词:
immunization;
low and middle-income countries;
maternal;
rotavirus;
ENVIRONMENTAL ENTERIC DYSFUNCTION;
ORAL POLIOVIRUS VACCINES;
SOUTH-AFRICAN CHILDREN;
T-CELL EPITOPE;
BREAST-MILK;
DOUBLE-BLIND;
MALAWIAN CHILDREN;
OPEN-LABEL;
IMMUNOGENICITY;
EFFICACY;
D O I:
10.1128/CVI.00405-16
中图分类号:
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号:
100102 ;
摘要:
The role of maternal immunity, received by infants either transplacentally or orally from breast milk, in rotavirus vaccine (RV) performance is evaluated here. Breastfeeding withholding has no effect on vaccine responses, but higher levels of transplacental rotavirus-specific IgG antibody contribute to reduced vaccine seroconversion. The gaps in knowledge on the factors associated with low RV efficacy in low- and middle-income countries (LMIC) remain, and further research is needed to shed more light on these issues.
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页数:8
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Zaman, K.
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ICDDR B, Dhaka 1000, Bangladesh ICDDR B, Dhaka 1000, Bangladesh

Sack, D. A.
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ICDDR B, Dhaka 1000, Bangladesh ICDDR B, Dhaka 1000, Bangladesh

Yunus, M.
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ICDDR B, Dhaka 1000, Bangladesh ICDDR B, Dhaka 1000, Bangladesh

Arifeen, S. E.
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ICDDR B, Dhaka 1000, Bangladesh ICDDR B, Dhaka 1000, Bangladesh

Podder, G.
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ICDDR B, Dhaka 1000, Bangladesh ICDDR B, Dhaka 1000, Bangladesh

Azim, T.
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ICDDR B, Dhaka 1000, Bangladesh ICDDR B, Dhaka 1000, Bangladesh

Luby, S.
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ICDDR B, Dhaka 1000, Bangladesh ICDDR B, Dhaka 1000, Bangladesh

Breiman, R. F.
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ICDDR B, Dhaka 1000, Bangladesh ICDDR B, Dhaka 1000, Bangladesh

Neuzil, K.
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PATH Rotavirus Vaccine Program, Seattle, WA USA ICDDR B, Dhaka 1000, Bangladesh

Datta, S. K.
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GlaxoSmithKline Biol, Rixensart, Belgium ICDDR B, Dhaka 1000, Bangladesh

Delem, A.
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GlaxoSmithKline Biol, Rixensart, Belgium ICDDR B, Dhaka 1000, Bangladesh

Suryakiran, P. V.
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GlaxoSmithKline Biol, Rixensart, Belgium ICDDR B, Dhaka 1000, Bangladesh

Bock, H. L.
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GlaxoSmithKline Biol, Rixensart, Belgium ICDDR B, Dhaka 1000, Bangladesh