Dihydrostilbene Derivatives from the Mongolian Medicinal Plant Scorzonera radiata

被引：28

作者：

Wang, Yao ^{[1
]}

Edrada-Ebel, RuAngelie ^{[2
]}

Tsevegsuren, Nanzad ^{[4
]}

Sendker, Jandirk ^{[1
]}

Braun, Manfred ^{[3
]}

Wray, Victor ^{[5
]}

Lin, Wenhan ^{[6
]}

Proksch, Peter ^{[1
]}

机构：

[1] Univ Dusseldorf, Inst Pharmazeut Biol & Biotechnol, D-40225 Dusseldorf, Germany

[2] Univ Strathclyde, Strathclyde Inst Pharm & Biomed Sci, Glasgow G4 0NR, Lanark, Scotland

[3] Univ Dusseldorf, Inst Organ & Makromol Chem 1, D-40225 Dusseldorf, Germany

[4] Natl Univ Mongolia, Fac Chem, Dept Organ & Food Chem, Ulaanbaatar, Mongolia

[5] Helmholtz Zentrum Infekt Forsch GmbH, D-38124 Braunschweig, Germany

[6] Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 04期

关键词：

TYROLOBIBENZYLS; ACID;

D O I：

10.1021/np800782f

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Chromatographic separation of a crude extract obtained from aerial parts of the Mongolian medicinal plant Scorzonera radiata yielded five new dihydrostilbenes, scorzodihydrostilbenes A-E (1-5). The structures were unambiguously elucidated on the basis of one- and two-dimensional NMR (H-1, C-13, COSY, HMBC, HMQC, and ROESY) and mass spectrometric data. Compounds 1-5 exhibited antioxidative activity when analyzed in the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. For 1 and 5 the antioxidant activities were stronger than that of the well-known naturally occurring stilbene antioxidant resveratrol.

引用

页码：671 / 675

页数：5

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