Usefulness of transabdominal ultrasonography for assessing ulcerative colitis: a prospective, multicenter study

被引：45

作者：

Kinoshita, Kenji ^{[1
]}

Katsurada, Takehiko ^{[1
]}

Nishida, Mutsumi ^{[2
,3
]}

Omotehara, Satomi ^{[2
,3
]}

Onishi, Reizo ^{[1
]}

Mabe, Katsuhiro ^{[4
]}

Onodera, Aki ^{[5
]}

Sato, Mami ^{[5
]}

Eto, Kazunori ^{[6
]}

Suya, Mitsutoshi ^{[7
]}

Maemoto, Atsuo ^{[8
]}

Hasegawa, Toru ^{[9
]}

Yamamoto, Junji ^{[10
]}

Mitsumori, Daiki ^{[11
]}

Yoshii, Shinji ^{[12
]}

Ono, Kota ^{[13
]}

Sakamoto, Naoya ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Med, Dept Gastroenterol & Hepatol, Kita Ku, Kita 15,Nishi 7, Sapporo, Hokkaido 0608638, Japan

[2] Hokkaido Univ Hosp, Div Lab & Transfus Med, Sapporo, Hokkaido, Japan

[3] Hokkaido Univ Hosp, Diagnost Ctr Sonog, Sapporo, Hokkaido, Japan

[4] Natl Hosp Org Hakodate Hosp, Dept Gastroenterol, Hakodate, Hokkaido, Japan

[5] Tomakomai City Hosp, Dept Clin Lab, Tomakomai, Japan

[6] Tomakomai City Hosp, Dept Gastroenterol, Tomakomai, Japan

[7] Sapporo Higashi Tokushukai Hosp, Dept Clin Lab, Sapporo, Hokkaido, Japan

[8] Sapporo Higashi Tokushukai Hosp, Inflammatory Bowel Dis Ctr, Sapporo, Hokkaido, Japan

[9] Ohguro Gastroenterol Hosp, Dept Clin Lab, Sapporo, Hokkaido, Japan

[10] Ohguro Gastroenterol Hosp, Sapporo, Hokkaido, Japan

[11] Sapporo Med Ctr NTT EC, Dept Clin Lab, Sapporo, Hokkaido, Japan

[12] Sapporo Med Ctr NTT EC, Dept Gastroenterol, Sapporo, Hokkaido, Japan

[13] Hokkaido Univ Hosp, Clin Res & Med Innovat Ctr, Sapporo, Hokkaido, Japan

来源：

JOURNAL OF GASTROENTEROLOGY | 2019年 / 54卷 / 06期

关键词：

Ulcerative colitis; Transabdominal ultrasonography; Colonoscopy; INFLAMMATORY-BOWEL-DISEASE; CONTRAST-ENHANCED ULTRASONOGRAPHY; MAGNETIC-RESONANCE COLONOGRAPHY; CROHNS-DISEASE; X-RAY; ULTRASOUND; MANAGEMENT; DIAGNOSIS; WALL; REMISSION;

D O I：

10.1007/s00535-018-01534-w

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

BackgroundTransabdominal ultrasonography (US) has been reported to be a useful tool for evaluating ulcerative colitis (UC) although with less well-established data than for Crohn's disease. This prospective multicenter study aimed to establish the usefulness of US compared with colonoscopy (CS) for assessing disease extent and activity of UC.MethodsAltogether, 173 patients with UC were prospectively enrolled, among whom 156 were eligible for this study. All patients underwent US and CS within 2days at five facilities. We divided the colon into six segments and examined each segment and the rectum using US and CS. US severity was graded 1-4 regarding bowel wall thickness, stratification, and ulceration. CS severity was also graded 1-4 according to Matts' endoscopic classification. Concordance between US and CS grades for all colonic segments was analyzed using kappa statistics. US and CS findings were also compared with the clinical disease activity index (CAI) and histological grade using Spearman's correlation coefficient.ResultsThere was moderate concordance between US and CS grades in all colonic segments (weighted =0.55, p<0.001). Concordance was rated moderate for each colonic segment but only slight for the rectum. The US grade was significantly correlated with the CAI score (r=0.40, p<0.001) and histological grade (r=0.35, p<0.001).ConclusionsThis prospective multicenter study showed moderate concordance between US and CS for assessing the disease activity of UC. Hence, US may be used more generally for evaluating UC in daily clinical practice.

引用

页码：521 / 529

页数：9

共 44 条

[1] Magnetic resonance colonography for the detection of inflammatory diseases of the large bowel: quantifying the inflammatory activity [J].