Central Cemento-Ossifying Fibroma: Primary Odontogenic or Osseous Neoplasm?

被引：20

作者：

Woo, Sook-Bin ^{[1
,2
,3
]}

机构：

[1] Harvard Univ, Sch Dent Med, Dept Oral Med Infect & Immun, Boston, MA 02115 USA

[2] Brigham & Womens Hosp, Div Oral Med & Dent, Clin Affairs, Boston, MA 02115 USA

[3] Brigham & Womens Hosp, Dept Pathol, Boston, MA 02115 USA

来源：

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 2015年 / 73卷 / 12期

关键词：

MCCUNE-ALBRIGHT-SYNDROME; FAMILIAL GIGANTIFORM CEMENTOMA; FIBROOSSEOUS LESIONS; SCLEROSING OSTEOMYELITIS; DISTINGUISHING FEATURES; DIFFERENTIAL-DIAGNOSIS; NATURAL-HISTORY; DYSPLASIA; JUVENILE; BONE;

D O I：

10.1016/j.joms.2015.05.010

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Currently, central cemento-ossifying fibroma is classified by the World Health Organization as a primary bone-forming tumor of the jaws. However, histopathologically, it is often indistinguishable from cemento-osseous dysplasias in that it forms osteoid and cementicles (cementum droplets) in varying proportions. It is believed that pluripotent cells within the periodontal membrane can be stimulated to produce either osteoid or woven bone and cementicles when stimulated. If this is true, cemento-ossifying fibroma would be better classified as a primary odontogenic neoplasm arising from the periodontal ligament. Cemento-ossifying fibromas also do not occur in the long bones. The present report compares several entities that fall within the diagnostic realm of benign fibro-osseous lesions and reviews the evidence for reclassifying central cemento-ossifying fibroma as a primary odontogenic neoplasm. (C) 2015 American Association of Oral and Maxillofacial Surgeons

引用

页码：S87 / S93

页数：7

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