Water efficiency and safe re-use of different grades of water - Topical issues for the pharmaceutical industry

被引:17
作者
Strade, Elina [1 ,2 ]
Kalnina, Daina [1 ]
Kulczycka, Joanna [3 ]
机构
[1] Riga Tech Univ, Fac Mat Sci & Appl Chem, Inst Gen Chem Engn, Paula Valdena Iela 3-7, LV-1048 Riga, Latvia
[2] JSC Grindeks, Krustpils Iela 53, LV-1057 Riga, Latvia
[3] Mineral & Energy Econ Res Inst, J Wybickiego 7A, Krakow, Poland
关键词
Pharmaceutical industry; Safe water re-use; Circular economy; Water quality; Resource recovery; WASTE-WATER; RADIATION-CHEMISTRY; RISK-ASSESSMENT; REMOVAL; TECHNOLOGIES; MANAGEMENT; TOXICITY; SYSTEM; IMPACT; USAGE;
D O I
10.1016/j.wri.2020.100132
中图分类号
TV21 [水资源调查与水利规划];
学科分类号
081501 ;
摘要
The pharmaceutical industry is a highly water-dependent economic sector and requires different degrees of water purity. The study presents an overview of the current water quality requirements, as well as limitations and safety considerations for water re-use in pharmaceutical manufacturing. Several principles for implementing circular economy elements into pharmaceutical wastewater treatment procedures are described: the use of recovered solvents as an easily degradable carbon source for the denitrification process, the use of phosphorus-containing wastewater as a nutrient source for activated sludge microorganisms, the use of inorganic acids and bases for pH control in wastewater treatment processes, and the use of Al3+ containing wastewater as a coagulant. The case study indicates that specific wastewater streams can be reused as secondary materials if the chemical composition of wastewater from pharmaceutical batch processing is well constrained and separate collection is ensured.
引用
收藏
页数:16
相关论文
共 82 条
  • [11] Asfaw T., 2018, J Res Environ Sci Toxicol, V7, P7, DOI [10.14303/jrest.2018.020, DOI 10.14303/JREST.2018.020]
  • [12] Awaleh M. O., 2014, Hydrology: Current Research, V5, P164
  • [13] Radiation chemistry of salicylic and methyl substituted salicylic acids: Models for the radiation chemistry of pharmaceutical compounds
    Ayatollahi, Shakiba
    Kalnina, Daina
    Song, Weihua
    Turks, Mans
    Cooper, William J.
    [J]. RADIATION PHYSICS AND CHEMISTRY, 2013, 92 : 93 - 98
  • [14] Recent advances in structure and reactivity of dissolved organic matter: radiation chemistry of non-isolated natural organic matter and selected model compounds
    Ayatollahi, Shakiba
    Kalnina, Daina
    Song, Weihua
    Cottrell, Barbara A.
    Gonsior, Michael
    Cooper, William J.
    [J]. WATER SCIENCE AND TECHNOLOGY, 2012, 66 (09) : 1941 - 1949
  • [15] Environmental performance of wastewater reuse systems: impact of system boundaries and external conditions
    Baresel, Christian
    Dalgren, Lena
    Almemark, Mats
    Lazic, Aleksandra
    [J]. WATER SCIENCE AND TECHNOLOGY, 2016, 73 (06) : 1387 - 1394
  • [16] Bhatia A., 2015, COOLING WATER PROBLE
  • [17] Byrne F. P., 2016, SUSTAINABLE CHEM PRO, V4, P7, DOI [10.1186/s40508-016-0051-z, DOI 10.1186/S40508-016-0051-Z]
  • [18] TOXICITY TESTS FOR ENSURING SUCCESFUL INDUSTRIAL WASTEWATER TREATMENT PLANT OPERATION
    Cebere, B.
    Faltina, E.
    Zelcans, N.
    Kalnina, D.
    [J]. ENVIRONMENTAL AND CLIMATE TECHNOLOGIES, 2009, 3 (03) : 41 - +
  • [19] Treatment of real pharmaceutical wastewater using combined approach of Fenton applications and aerobic biological treatment
    Changotra, Rahil
    Rajput, Himadri
    Dhir, Amit
    [J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2019, 376 : 175 - 184
  • [20] Cleary J.G., 2006, P WATER ENV FED, V13, P111