Unamplified gene sensing via Cas9 on graphene

被引：21

作者：

Bruch, Richard ^{[1
,2
]}

Urban, Gerald A. ^{[1
,3
]}

Dincer, Can ^{[1
,2
,4
]}

机构：

[1] Univ Freiburg, Dept Microsyst Engn IMTEK, Lab Sensors, Freiburg, Germany

[2] Univ Freiburg, Freiburg Ctr Interact Mat & Bioinspired Technol F, Freiburg, Germany

[3] Univ Freiburg, Freiburg Mat Res Ctr FMF, Freiburg, Germany

[4] Imperial Coll London, Royal Sch Mines, Dept Bioengn, London, England

来源：

NATURE BIOMEDICAL ENGINEERING | 2019年 / 3卷 / 06期

关键词：

FIELD-EFFECT TRANSISTOR;

D O I：

10.1038/s41551-019-0413-4

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

An electrical biosensor that relies on the binding of target nucleic acid sequences to Cas9 immobilized on a graphene field-effect transistor enables the rapid detection of mutations in purified samples without the need for nucleic acid amplification. © 2019, Springer Nature Limited.

引用

页码：419 / 420

页数：2

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