Making a case "for" focal therapy of the prostate in intermediate risk prostate cancer: current perspective and ongoing trials

被引：10

作者：

Wang, Alex Z. ^{[1
]}

Lebastchi, Amir H. ^{[1
,9
]}

O'Connor, Luke P. ^{[1
]}

Ahdoot, Michael ^{[1
]}

Mehralivand, Sherif ^{[2
]}

Yerram, Nitin ^{[1
]}

Taneja, Samir S. ^{[3
]}

George, Arvin K. ^{[4
]}

Sanchez-Salas, Rafael ^{[5
,6
]}

Ward, John F. ^{[7
]}

Laguna, Pilar ^{[8
]}

de la Rosette, Jean ^{[8
]}

Pinto, Peter A. ^{[1
]}

机构：

[1] NCI, Urol Oncol Branch, NIH, Bethesda, MD 20892 USA

[2] NCI, Mol Imaging Branch, NIH, Bethesda, MD 20892 USA

[3] NYU, Sch Med, Dept Urol, Div Urol Oncol,NYU Langone Hlth, New York, NY 10003 USA

[4] Michigan Med, Dept Urol, Ann Arbor, MI USA

[5] Inst Mutualiste Montsouris, Dept Urol, Paris, France

[6] Univ Paris 05, Paris, France

[7] Univ Texas MD Anderson Canc Ctr, Dept Urol, Houston, TX 77030 USA

[8] Istanbul Medipol Univ, Dept Urol, Istanbul, Turkey

[9] 10 Ctr Dr,Bldg 10,Room 1-5950, Bethesda, MD 20892 USA

来源：

WORLD JOURNAL OF UROLOGY | 2021年 / 39卷 / 03期

关键词：

Focal therapy; prostate cancer; MRI; WHOLE-GLAND CRYOTHERAPY; RADICAL PROSTATECTOMY; LASER-ABLATION; ACTIVE SURVEILLANCE; UNITED-STATES; INDEX LESION; FOLLOW-UP; OUTCOMES; MORTALITY; RADIATION;

D O I：

10.1007/s00345-020-03525-0

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Focal therapy is growing as an alternative management options for men with clinically localized prostate cancer. Parallel to the increasing popularity of active surveillance (AS) as a treatment for low-risk disease, there has been an increased interest towards providing focal therapy for patients with intermediate-risk disease. Focal therapy can act as a logical "middle ground" in patients who seek treatment while minimizing potential side effects of definitive whole-gland treatment. The aim of the current review is to define the rationale of focal therapy in patients with intermediate-risk prostate cancer and highlight the importance of patient selection in focal therapy candidacy.

引用

页码：729 / 739

页数：11