Synthesis of Amaryllidaceae alkaloids, siculine, oxocrinine, epicrinine, and buflavine

被引：38

作者：

Kodama, S ^{[1
]}

Takita, H ^{[1
]}

Kajimoto, T ^{[1
]}

Nishide, K ^{[1
]}

Node, M ^{[1
]}

机构：

[1] Kyoto Pharmaceut Univ, Dept Pharmaceut Mfg Chem, Yamashina Ku, Kyoto 6078412, Japan

来源：

TETRAHEDRON | 2004年 / 60卷 / 22期

关键词：

phenol coupling; phenyliodine(III) bis(trifluoroacete) (PIFA); siculine; oxocrinine; epicrinine; buflavine;

D O I：

10.1016/j.tet.2004.03.087

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three crinane type of alkaloids isolated from Amaryllidaceae family were synthesized by taking advantage of the PIFA-mediated intramolecular p-p' diphenol coupling reaction of norbelladine derivatives. Furthermore, buflavine was also prepared by using the p-p' diphenol coupling followed by dienone-phenol rearrangement as a key step. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：4901 / 4907

页数：7

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