Peripheral primitive neuroectodermal tumor involving the paravertebral and retroperitoneal regions

被引:7
作者
Fukumoto, S [1 ]
Takamura, K [1 ]
Nakanishi, K [1 ]
Yamamoto, M [1 ]
Inaba, S [1 ]
Makimura, S [1 ]
Yoshikawa, T [1 ]
Terai, T [1 ]
机构
[1] OBIHIRO KOHSEI HOSP,DEPT MED 1,OBIHIRO,HOKKAIDO 080,JAPAN
关键词
translocation (11; 22)(q24; q12); neurosecretory granules;
D O I
10.2169/internalmedicine.36.424
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A rare case of peripheral primitive neuroectodermal tumor (PNET) is reported. A 68-year-old woman complaining of lumbago was admitted to our hospital, Diagnosis was made based on pathological findings characterized by Homer Wright-type rosettes, Ultrastructural examination showed the presence of neurosecretory granules and short cytoplasmic processes, which were highly suggestive of neural differentiation. Chromosomal analysis of the neoplastic cells revealed translocation (11;22)(q24;q12), which is often found in Ewing's sarcoma and Askin tumor, These results strengthen the hypothesis of a common histogenesis for these small round cell tumors, and suggest common oncogenesis for these neoplasms.
引用
收藏
页码:424 / 429
页数:6
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