Peripheral primitive neuroectodermal tumor involving the paravertebral and retroperitoneal regions

被引：7

作者：

Fukumoto, S ^{[1
]}

Takamura, K ^{[1
]}

Nakanishi, K ^{[1
]}

Yamamoto, M ^{[1
]}

Inaba, S ^{[1
]}

Makimura, S ^{[1
]}

Yoshikawa, T ^{[1
]}

Terai, T ^{[1
]}

机构：

[1] OBIHIRO KOHSEI HOSP,DEPT MED 1,OBIHIRO,HOKKAIDO 080,JAPAN

来源：

INTERNAL MEDICINE | 1997年 / 36卷 / 06期

关键词：

translocation (11; 22)(q24; q12); neurosecretory granules;

D O I：

10.2169/internalmedicine.36.424

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A rare case of peripheral primitive neuroectodermal tumor (PNET) is reported. A 68-year-old woman complaining of lumbago was admitted to our hospital, Diagnosis was made based on pathological findings characterized by Homer Wright-type rosettes, Ultrastructural examination showed the presence of neurosecretory granules and short cytoplasmic processes, which were highly suggestive of neural differentiation. Chromosomal analysis of the neoplastic cells revealed translocation (11;22)(q24;q12), which is often found in Ewing's sarcoma and Askin tumor, These results strengthen the hypothesis of a common histogenesis for these small round cell tumors, and suggest common oncogenesis for these neoplasms.

引用

页码：424 / 429

页数：6

共 28 条

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