Steroidal Saponins from Asparagus racemosus

被引:28
作者
Sharma, Upendra [1 ]
Saini, Rikki [1 ]
Kumar, Bobita Neeraj [1 ]
Singh, Bikram [1 ]
机构
[1] CSIR, Inst Himalayan Bioresource Technol, Nat Plant Prod Div, Palampur 176061, Himachal Prades, India
关键词
Asparagus racemosus; steroidal saponin; shatavaroside A; shatavaroside B; AYURVEDIC CRUDE DRUGS; CHEMISTRY; ROOT;
D O I
10.1248/cpb.57.890
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Two new steroidal saponins, shatavaroside A (1) and shatavaroside B (2) together with a known saponin, filiasparoside C, were isolated from the roots of Asparagus racemosus. Filiasparoside C was first time isolated from this plant. Their structures were elucidated by I D and 2D NMR experiments including correlation spectroscopy, distortionless enhancement by polarization transfer, heteronuclear multiple quantum correlation and heteronuclear multiple bond coherence spectroscopy as well as electrospray ionization-QTOF-MS/MS analysis.
引用
收藏
页码:890 / 893
页数:4
相关论文
共 24 条
[1]  
Agrawal PK, 1997, MAGN RESON CHEM, V35, P441, DOI 10.1002/(SICI)1097-458X(199707)35:7<441::AID-OMR104>3.0.CO
[2]  
2-Q
[3]   Bacosterol glycoside, 2 new 13,14-seco-steiroid glycoside from Bacopa monnieri [J].
Bhandari, P ;
Kumar, N ;
Singh, B ;
Kaul, VK .
CHEMICAL & PHARMACEUTICAL BULLETIN, 2006, 54 (02) :240-241
[4]   Cucurbitacins from Bacopa monnieri [J].
Bhandari, Pamita ;
Kumar, Neeraj ;
Singh, Bikram ;
Kaul, Vijay K. .
PHYTOCHEMISTRY, 2007, 68 (09) :1248-1254
[5]   Asparagus racemosus -: Ethnopharmacological evaluation and conservation needs [J].
Bopana, Nishritha ;
Saxena, Sanjay .
JOURNAL OF ETHNOPHARMACOLOGY, 2007, 110 (01) :1-15
[6]  
Chadda YR, 2003, WELTH INDIA DICT IND, VIA, P470
[7]   Immunoadjuvant potential of Asparagus racemosus aqueous extract in experimental system [J].
Gautam, M ;
Diwanay, S ;
Gairola, S ;
Shinde, Y ;
Patki, P ;
Patwardhan, B .
JOURNAL OF ETHNOPHARMACOLOGY, 2004, 91 (2-3) :251-255
[8]  
Goyal R K, 2003, Indian J Med Sci, V57, P408
[9]   Asparinins, asparosides, curillins, curillosides and shavatarins:: structural clarification with the isolation of shatavarin V, a new steroidal saponin from the root of Asparagus racemosus [J].
Hayes, Patricia Y. ;
Jahidin, Aisyah H. ;
Lehmann, Reg ;
Penman, Kerry ;
Kitching, William ;
De Voss, James J. .
TETRAHEDRON LETTERS, 2006, 47 (49) :8683-8687
[10]   STUDIES IN STEROID METABOLISM .17. THE INFRARED ABSORPTION SPECTRA OF THE STEROID SAPOGENINS [J].
JONES, RN ;
KATZENELLENBOGEN, E ;
DOBRINER, K .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1953, 75 (01) :158-166