The Risk of Osteoporotic Fractures According to the FRAX Model in Korean Patients the Rheumatoid Arthritis

被引:16
作者
Lee, Jae Ho [1 ]
Suh, Young Sun [1 ]
Koh, Jung Hee [1 ]
Jung, Seung-Min [1 ]
Lee, Jennifer Jooha [1 ]
Kwok, Seung-Ki [1 ]
Ju, Ji Hyeon [1 ]
Park, Kyung-Su [1 ]
Park, Sung-Hwan [1 ]
机构
[1] Catholic Univ Korea, Seoul St Marys Hosp, Sch Med, Div Rheumatol,Dept Internal Med, Seoul 137040, South Korea
关键词
Arthritis; Rheumatoid; Osteoporosis; Fractures; Bone; BMD; FRAX; BONE-MINERAL DENSITY; POPULATION-BASED COHORT; POSTMENOPAUSAL OSTEOPOROSIS; ELDERLY-MEN; WOMEN; STRENGTH; TRIAL; SIZE; UK;
D O I
10.3346/jkms.2014.29.8.1082
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The aim of the current study is to identify patients without osteoporosis who met the criteria of the fracture risk assessment tool (FRAX) of the National Osteoporosis Foundation (NOF) only The incidence of fractures was investigated in patients who met only the FRAX criteria of the NOF and patients who presented osteoporosis. Five hundred and forty five patients with rheumatoid arthritis who visited a single center were recruited in Korea. In the follow-up period of median 30 months, the new onset of fractures was investigated. Of 223 patients who have no osteoporosis, 39 (17.4%) satisfied the FRAX criteria for pharmacological intervention. During the follow-up period, 2 new onset fractures occurred in patients who met only the FRAX criteria and 22 new onset fractures did in patients with osteoporosis by bone mineral density. The incidence rate for new onset fractures of patients who met only the FRAX criteria was with 295.93 per 10,000 person-years higher than in the general population with 114.99 per 10,000 person-years. Patients who met the FRAX criteria of the NOF only need pharmacological intervention because their numbers of incidence for new onset fractures are similar to those of patients with osteoporosis by BMD.
引用
收藏
页码:1082 / 1089
页数:8
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