18F-FDG PET/CT Findings in Cytomegalovirus Colitis

被引：5

作者：

Kjaer, Anna Sophie L. ^{[1
]}

Ribberholt, Iben ^{[1
]}

Thomsen, Kim ^{[2
]}

Ibsen, Per H. ^{[3
]}

Markova, Elena ^{[4
]}

Graff, Jesper ^{[5
]}

机构：

[1] Copenhagen Univ Hosp Hvidovre, Dept Infect Dis, Kettegaards Alle 30, DK-2650 Hvidovre, Denmark

[2] Copenhagen Univ Hosp, Rigshosp, Dept Clin Microbiol, Blegdamsvej 9, DK-2100 Copenhagen O, Denmark

[3] Copenhagen Univ Hosp Hvidovre, Dept Patol, Kettegaards Alle 30, DK-2650 Hvidovre, Denmark

[4] Copenhagen Univ Hosp Hvidovre, Dept Radiol, Kettegaards Alle 30, DK-2650 Hvidovre, Denmark

[5] Copenhagen Univ Hosp Hvidovre, Dept Clin Physiol & Nucl Med, Kettegaards Alle 30, DK-2650 Hvidovre, Denmark

来源：

DIAGNOSTICS | 2018年 / 9卷 / 01期

关键词：

F-18-FDG PET; CT; cytomegalovirus colitis; inflammatory bowel disease; INFLAMMATORY-BOWEL-DISEASE; INFECTION;

D O I：

10.3390/diagnostics9010003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present a case demonstrating the diagnostic work-up of a patient undergoing azathioprine treatment for inflammatory bowel disease (IBD), diagnosed with an acute cytomegalovirus (CMV) infection and CMV colitis. An F-18-FDG positron emission tomography/computed tomography (PET/CT) performed 2 weeks after debut of symptoms revealed pathological F-18-FDG uptake in the left side of the colon mucosa, mimicked activity of IBD. However, a diagnosis of CMV colitis was based on the presence of CMV IgM antibodies, a seroconversion of CMV IgG antibodies, presence of CMV DNA in plasma and the finding af CMV DNA in biopsies from the intestinal mucosa. The patient responded to treatment with ganciclovir. This case highlights that a positive F-18-FDG PET/CT scan of the colon can be due to CMV colitis.

引用

页数：3

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