Myc degradation: Dancing with ubiquitin ligases

被引:62
作者
Amati, B [1 ]
机构
[1] European Inst Oncol, Dept Expt Oncol, I-20141 Milan, Italy
关键词
D O I
10.1073/pnas.0403046101
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
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页码:8843 / 8844
页数:2
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共 26 条
[1]   Function of the c-Myc oncoprotein in chromatin remodeling and transcription [J].
Amati, B ;
Frank, SR ;
Donjerkovic, D ;
Taubert, S .
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2001, 1471 (03) :M135-M145
[2]   c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover [J].
Bahram, F ;
von der Lehr, N ;
Cetinkaya, C ;
Larsson, LG .
BLOOD, 2000, 95 (06) :2104-2110
[3]   The c-myc transactivation domain is a direct modulator of apoptotic versus proliferative signals [J].
Chang, DW ;
Claassen, GF ;
Hann, SR ;
Cole, MD .
MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (12) :4309-4319
[4]   Deconstructing Myc [J].
Eisenman, RN .
GENES & DEVELOPMENT, 2001, 15 (16) :2023-2030
[5]   Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation [J].
Frank, SR ;
Schroeder, M ;
Fernandez, P ;
Taubert, S ;
Amati, B .
GENES & DEVELOPMENT, 2001, 15 (16) :2069-2082
[6]   Phosphorylation by glycogen synthase kinase-3 controls c-Myc proteolysis and subnuclear localization [J].
Gregory, MA ;
Qi, Y ;
Hann, SR .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (51) :51606-51612
[7]   Skp2 is oncogenic and overexpressed in human cancers [J].
Gstaiger, M ;
Jordan, R ;
Lim, M ;
Catzavelos, C ;
Mestan, J ;
Slingerland, J ;
Krek, W .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (09) :5043-5048
[8]   MAP KINASE BINDS TO THE NH2-TERMINAL ACTIVATION DOMAIN OF C-MYC [J].
GUPTA, S ;
DAVIS, RJ .
FEBS LETTERS, 1994, 353 (03) :281-285
[9]   Enumeration of the simian virus 40 early region elements necessary for human cell transformation [J].
Hahn, WC ;
Dessain, SK ;
Brooks, MW ;
King, JE ;
Elenbaas, B ;
Sabatini, DM ;
DeCaprio, JA ;
Weinberg, RA .
MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (07) :2111-2123
[10]   Skp2 regulates Myc protein stability and activity [J].
Kim, SY ;
Herbst, A ;
Tworkowski, KA ;
Salghetti, SE ;
Tansey, WP .
MOLECULAR CELL, 2003, 11 (05) :1177-1188