Compact, low-cost NMR spectrometer and probe for dissolution DNP

被引：4

作者：

Albannay, Mohammed M. ^{[1
]}

Vinther, Joachim M. O. ^{[1
]}

Petersen, Jan Raagaard ^{[1
]}

Zhurbenko, Vitaliy ^{[1
]}

Ardenkjaer-Larsen, Jan Henrik ^{[1
,2
]}

机构：

[1] Tech Univ Denmark, Dept Hlth Technol, Ctr Hyperpolarizat Magnet Resonance, Orsteds Plads, DK-2800 Lyngby, Denmark

[2] GE Healthcare, Brondby, Denmark

来源：

JOURNAL OF MAGNETIC RESONANCE | 2019年 / 304卷

基金：

新加坡国家研究基金会;

关键词：

Dissolution DNP; NMR spectrometer; DNP probe; Solid-state NMR; DYNAMIC NUCLEAR-POLARIZATION; QUICK MEASUREMENT; COIL SENSITIVITY; REMOTE;

D O I：

10.1016/j.jmr.2019.04.016

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The desire for higher magnetic resonance sensitivity has led to the development of multiple home-built and commercial dissolution dynamic nuclear polarization polarizers. The emergence of polarizers capable of variable magnetic field strengths desires a versatile standalone spectrometer and NMR circuit to fulfill detection needs at different frequencies. We present a benchtop NMR spectrometer with a duplexer capable of serving high-field solid and liquid state NMR applications up to 450 MHz. A detailed view of the employed probe is discussed. Tuning and matching schemes are investigated yielding and experimentally verifying closed-form equations to estimate the nutation frequency for a remotely tuned and matched sample coil. (C) 2019 Elsevier Inc. All rights reserved.

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收藏

页码：7 / 15

页数：9

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