Saliva as a Future Field in Psoriasis Research

被引：24

作者：

Asa'ad, Farah ^{[1
]}

Fiore, Marco ^{[2
]}

Alfieri, Aniello ^{[2
]}

Pigatto, Paolo Daniele Maria ^{[3
]}

Franchi, Chiara ^{[3
]}

Berti, Emilio ^{[4
]}

Maiorana, Carlo ^{[5
]}

Damiani, Giovanni ^{[3
,4
,6
]}

机构：

[1] Univ Milan, Dept Biomed Surg & Dent Sci, I-20122 Milan, Italy

[2] Univ Campania Luigi Vanvitelli, Dept Women Child & Gen & Specialized Surg, I-80138 Naples, Italy

[3] Univ Milan, IRCCS Galeazzi Orthopaed Inst, Dept Biomed Surg & Dent Sci, Clin Dermatol, I-20126 Milan, Italy

[4] Univ Milan, Osped Maggiore Policlin, Dipartimento Fisiopatol Med Chirurg & Trapianti, Unita Operat Dermatol,IRCCS Fdn Ca Granda, I-20122 Milan, Italy

[5] Univ Milan, Ctr Jawbone Atrophies Policlin Hosp, Sch Dent, I-20122 Milan, Italy

[6] GISED, YDIN, I-24122 Bergamo, Italy

来源：

BIOMED RESEARCH INTERNATIONAL | 2018年 / 2018卷

关键词：

PERIODONTAL-DISEASE; DENTAL-CARIES; SERUM; FLUID; METHOTREXATE; PEMPHIGUS; CYCLOSPORINE; INFLAMMATION; SECRETION; LYSOZYME;

D O I：

10.1155/2018/7290913

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Psoriasis is a skin inflammatory disease characterized by an increased body of comorbidities, including parodontopathy. Despite the visibility of skin lesions, prognostic biomarkers, related to disease monitoring and therapeutic effectiveness, are still missing. Although several markers have been studied, none of them has been identified as an independent prognostic factor. This concise review aims to summarize the current knowledge and results in saliva research applied to psoriasis. Combination of different markers could improve the prognostic prediction in patients with psoriasis. Future studies are needed to implement research on salivary biomarkers and their prognostic/therapeutic effects in the management of patients with psoriasis.

引用

页数：6

共 50 条

[41] Enhancement of gingival inflammation induced by synergism of IL-1β and IL-6 [J].

Sawada, Shunsuke ;

Chosa, Naoyuki ;

Ishisaki, Akira ;

Naruishi, Koji .

BIOMEDICAL RESEARCH-TOKYO, 2013, 34 (01) :31-40

[42] LACK OF CORRELATION BETWEEN METHOTREXATE CONCENTRATIONS IN SERUM, SALIVA AND SWEAT AFTER 24-H METHOTREXATE INFUSIONS [J].

SCHRODER, H ;

JENSEN, KB ;

BRANDSBORG, M .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1987, 24 (04) :537-541

[43] The oral mucosal and salivary microbial community of Behcet's syndrome and recurrent aphthous stomatitis [J].

Seoudi, Noha ;

Bergmeier, Lesley A. ;

Drobniewski, Francis ;

Paster, Bruce ;

Fortune, Farida .

JOURNAL OF ORAL MICROBIOLOGY, 2015, 7 :1-9

[44] Measurement of 5-methoxypsoralen and 8-methoxypsoralen in saliva of PUVA patients as a noninvasive, clinically relevant alternative to monitoring in blood [J].

Shephard, SE ;

Zogg, M ;

Burg, G ;

Panizzon, RG .

ARCHIVES OF DERMATOLOGICAL RESEARCH, 1999, 291 (09) :491-499

[45]

Soudan RA, 2011, SAUDI MED J, V32, P386

[46] CHEMICAL-ANALYSIS OF PAROTID-SALIVA AND LACRIMAL FLUID IN PSORIATICS [J].

SYRJANEN, SM .

ARCHIVES OF DERMATOLOGICAL RESEARCH, 1983, 275 (03) :152-155

[47] Understanding salivary fluid and protein secretion [J].

Turner, RJ ;

Sugiya, H .

ORAL DISEASES, 2002, 8 (01) :3-11

[48]

Van Dyke T.-E., 2016, J PERIODONTOLOGY S, V84, pS1

[49]

Villanova F., 2013, ANN RHEUMATIC DIS S2, V72

[50] Serum and tissue expression of transforming growth factor beta 1 in psoriasis [J].

Zaher, H. ;

Shaker, O. G. ;

El-Komy, M. H. M. ;

El-Tawdi, A. ;

Fawzi, M. ;

Kadry, D. .

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2009, 23 (04) :406-409

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