Diagnosis of Heart Failure with Preserved Ejection Fraction

被引:20
作者
Wachter, Rolf [1 ]
Edelmann, Frank [1 ]
机构
[1] Univ Gottingen, Clin Cardiol & Pneumol, DZHK German Ctr Cardiovasc Res, D-37073 Gottingen, Germany
关键词
Heart failure with preserved ejection fraction; Diastolic heart failure; Diagnosis; Biomarkers; Echocardiographic; Diastolic dysfunction; EUROPEAN-SOCIETY; TASK-FORCE; SPIRONOLACTONE; HYPERTENSION; PREVALENCE; GUIDELINES; OUTCOMES;
D O I
10.1016/j.hfc.2014.04.010
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Heart failure with preserved ejection fraction (HFpEF) constitutes a growing health care burden worldwide. Although definitions vary somewhat among guidelines, in general the presence of typical heart failure symptoms and signs in combination with a preserved left ventricular ejection fraction (>= 50%) and functional and/or structural left ventricular changes makes the diagnosis likely. This review focuses on the current understanding of diagnostic criteria, as presented in current guidelines and consensus recommendations, and on new insights from recent papers. The role of comorbidities that often contribute to symptoms and hamper the HFpEF diagnostics is also reviewed.
引用
收藏
页码:399 / +
页数:9
相关论文
共 29 条
[1]  
Becher Peter Moritz, 2013, Expert Opin Med Diagn, V7, P463, DOI 10.1517/17530059.2013.825246
[2]   Rationale and design of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist Trial: A randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction [J].
Desai, Akshay S. ;
Lewis, Eldrin F. ;
Li, Rebecca ;
Solomon, Scott D. ;
Assmann, Susan F. ;
Boineau, Robin ;
Clausell, Nadine ;
Diaz, Rafael ;
Fleg, Jerome L. ;
Gordeev, Ivan ;
McKinlay, Sonja ;
O'Meara, Eileen ;
Shaburishvili, Tamaz ;
Pitt, Bertram ;
Pfeffer, Marc A. .
AMERICAN HEART JOURNAL, 2011, 162 (06) :966-U27
[3]   Effect of Spironolactone on Diastolic Function and Exercise Capacity in Patients With Heart Failure With Preserved Ejection Fraction The Aldo-DHF Randomized Controlled Trial [J].
Edelmann, Frank ;
Wachter, Rolf ;
Schmidt, Albrecht G. ;
Kraigher-Krainer, Elisabeth ;
Colantonio, Caterina ;
Kamke, Wolfram ;
Duvinage, Andre ;
Stahrenberg, Raoul ;
Durstewitz, Kathleen ;
Loeffler, Markus ;
Duengen, Hans-Dirk ;
Tschoepe, Carsten ;
Herrmann-Lingen, Christoph ;
Halle, Martin ;
Hasenfuss, Gerd ;
Gelbrich, Goetz ;
Pieske, Burkert .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2013, 309 (08) :781-791
[4]   Hemodynamic Responses to Rapid Saline Loading The Impact of Age, Sex, and Heart Failure [J].
Fujimoto, Naoki ;
Borlaug, Barry A. ;
Lewis, Gregory D. ;
Hastings, Jeffrey L. ;
Shafer, Keri M. ;
Bhella, Paul S. ;
Carrick-Ranson, Graeme ;
Levine, Benjamin D. .
CIRCULATION, 2013, 127 (01) :55-+
[5]   Guidelines for the diagnosis and treatment of pulmonary hypertension [J].
Galie, Nazzareno ;
Hoeper, Marius M. ;
Humbert, Marc ;
Torbicki, Adam ;
Vachiery, Jean-Luc ;
Albert Barbera, Joan ;
Beghetti, Maurice ;
Corris, Paul ;
Gaine, Sean ;
Gibbs, J. Simon ;
Angel Gomez-Sanchez, Miguel ;
Jondeau, Guillaume ;
Klepetko, Walter ;
Opitz, Christian ;
Peacock, Andrew ;
Rubin, Lewis ;
Zellweger, Michael ;
Simonneau, Gerald .
EUROPEAN HEART JOURNAL, 2009, 30 (20) :2493-2537
[6]   Relationship of Plasma Galectin-3 to Renal Function in Patients With Heart Failure: Effects of Clinical Status, Pathophysiology of Heart Failure, and Presence or Absence of Heart Failure [J].
Gopal, Deepa M. ;
Kommineni, Maya ;
Ayalon, Nir ;
Koelbl, Christian ;
Ayalon, Rivka ;
Biolo, Andreia ;
Dember, Laura M. ;
Downing, Jill ;
Siwik, Deborah A. ;
Liang, Chang-seng ;
Colucci, Wilson S. .
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2012, 1 (05) :e000760
[7]   Death in Heart Failure A Community Perspective [J].
Henkel, Danielle M. ;
Redfield, Margaret A. ;
Weston, Susan A. ;
Gerber, Yariv ;
Roger, Veronique L. .
CIRCULATION-HEART FAILURE, 2008, 1 (02) :91-97
[8]   Discriminating clinical features of heart failure with preserved vs. reduced ejection fraction in the community [J].
Ho, Jennifer E. ;
Gona, Philimon ;
Pencina, Michael J. ;
Tu, Jack V. ;
Austin, Peter C. ;
Vasan, Ramachandran S. ;
Kannel, William B. ;
D'Agostino, Ralph B. ;
Lee, Douglas S. ;
Levy, Daniel .
EUROPEAN HEART JOURNAL, 2012, 33 (14) :1734-1741
[9]   Diagnosis, Assessment, and Treatment of Non-Pulmonary Arterial Hypertension Pulmonary Hypertension [J].
Hoeper, Marius M. ;
Barbera, Joan Albert ;
Channick, Richard N. ;
Hassoun, Paul M. ;
Lang, Irene M. ;
Manes, Alessandra ;
Martinez, Fernando J. ;
Naeije, Robert ;
Olschewski, Horst ;
Pepke-Zaba, Joanna ;
Redfield, Margaret M. ;
Robbins, Ivan M. ;
Souza, Rogerio ;
Torbicki, Adam ;
McGoon, Michael .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 54 (01) :S85-S96
[10]   Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction A Community-Based Study [J].
Lam, Carolyn S. P. ;
Roger, Veronique L. ;
Rodeheffer, Richard J. ;
Borlaug, Barry A. ;
Enders, Felicity T. ;
Redfield, Margaret M. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 53 (13) :1119-1126