Amino Acid Amide based Ionic Liquid as an Efficient Organo-Catalyst for Solvent-free Knoevenagel Condensation at Room Temperature

被引：24

作者：

Burate, Pralhad A. ^{[1
,2
]}

Javle, Balasaheb R. ^{[1
,2
]}

Desale, Pranjal H. ^{[1
]}

Kinage, Anil K. ^{[1
,2
]}

机构：

[1] Natl Chem Lab, Chem Engn & Proc Dev Div, CSIR, Pune 411008, Maharashtra, India

[2] Acad Sci & Innovat Res AcSIR, New Delhi 110025, India

来源：

CATALYSIS LETTERS | 2019年 / 149卷 / 09期

关键词：

Ionic liquid; Amino acid amide; Knoevenagel condensation; Solvent-free; Acrylonitrile; Cyanoacrylate; GREEN PROCEDURE; DERIVATIVES;

D O I：

10.1007/s10562-019-02840-5

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Ionic liquids of amino acid amide were synthesized and used as an efficient catalyst for solvent-free Knoevenagel condensation. Synthesized ionic liquids are an environmentally benign, inexpensive, metal free and plays the dual role of solvent as well as an efficient catalyst for Knoevenagel condensation. A wide range of aliphatic, aromatic and heteroaromatic aldehydes easily undergo condensation with malononitrile and ethyl cyanoacetate. The reaction proceeds at room temperature without using any organic solvent and is very fast with good to excellent yield. Additionally, the catalyst is easily separable and recyclable without loss of activity. [GRAPHICS] .

引用

页码：2368 / 2375

页数：8

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