Reactivity of mixed organozinc and organocopper reagents. 3. Atom economic electrophilic amination of methyl arylzinc reagents

被引：16

作者：

Erdik, Ender ^{[1
]}

Pekel, Oezgen Oemuer ^{[1
]}

Kalkan, Melike ^{[1
]}

机构：

[1] Ankara Univ, Fac Sci, TR-06100 Ankara, Turkey

来源：

APPLIED ORGANOMETALLIC CHEMISTRY | 2009年 / 23卷 / 06期

关键词：

electrophilic amination; mixed arylzincs; acetone O-(mesitylenesulfonyl)oxime; arylamines; C-N coupling; CATALYTIC ASYMMETRIC-SYNTHESIS; CONJUGATE MICHAEL-ADDITIONS; DIORGANOZINC COMPOUNDS; ARYLATION; ALCOHOLS; ALDEHYDES; HALIDES; SUBSTITUTION; ARYLAMINES; NITROGEN;

D O I：

10.1002/aoc.1506

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Reaction of methyl arylzincs with acetone O-(mesitylenesulfonyl)oxime in THF in the presence of CuCN at room temperature is efficient in selective electrophilic amination of aryl carbanions. This procedure allows for the preparation of arylamines in moderate to good yields and provides an efficient and atom economic alternative to existing amination methods for diarylzincs. Copyright (C) 2009 John Wiley & Sons, Ltd.

引用

页码：245 / 248

页数：4

共 73 条

[1]

ANETIL EJG, 2002, J ORGANOMET CHEM, V653, P150

[2]

ASKANI R, 1996, COMPREHENSIVE ORGANI, V7, P1881

[3] Cuprous cyanide - A note on its preparation and use [J].