Residential radon and small cell lung cancer. A systematic review

被引:44
|
作者
Rodriguez-Martinez, Angeles [1 ,2 ]
Torres-Duran, Maria [2 ,3 ]
Barros-Dios, Juan M. [2 ,4 ,5 ]
Ruano-Ravina, Alberto [2 ,4 ]
机构
[1] Univ Hosp Complex Pontevedra, Serv Med Oncol, Pontevedra, Spain
[2] Univ Santiago de Compostela, Dept Prevent Med & Publ Hlth, Santiago De Compostela, Spain
[3] Univ Hosp Complex Vigo, Serv Neumol, Vigo, Spain
[4] CIBERESP, Madrid, Spain
[5] Univ Hosp Complex Santiago de Compostela, Serv Prevent Med, Santiago De Compostela, Spain
关键词
Lung neoplasms; Small cell lung cancer; Residential radon; Systematic review; INDOOR RADON; EXPOSURE; RISK; SURVEILLANCE; POPULATION; SMOKING;
D O I
10.1016/j.canlet.2018.04.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Residential radon exposure is considered the second cause of lung cancer and the first in never smokers. Nevertheless, the association between the different histological types of lung cancer and radon is not completely clear, and radon effect on small cell lung cancer is not completely understood. We aim to asses the effect of residential radon exposure on the risk of small cell lung cancer (SCLC) in general population and miners through a systematic review applying predefined inclusion and exclusion criteria. 16 studies were included. Most of them point to a relationship between indoor radon and SCLC, though some investigations show no association. When comparing the risk of SCLC due to radon exposure with NSCLC, it can be observed that an increased risk for SCLC is present. Small cell lung cancer seems to be the histological type of lung cancer most tightly related with residential radon. (C) 2018 Elsevier B.V. All rights reserved.
引用
收藏
页码:57 / 62
页数:6
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